Factors associated with pharmacological treatment in children with attention-deficit/hyperactivity disorders: a retrospective study of a series of 77 cases in a single third-level reference Centre in Apulia region
Abstract Background The present study analysed data on children and adolescents with a diagnosis of attention-deficit/hyperactivity disorder (ADHD) who were referred to the ADHD reference centre of Scientific Institute IRCCS E. Medea (Brindisi, Italy) for ADHD pharmacotherapy initiation and monitori...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-11-01
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| Series: | Italian Journal of Pediatrics |
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| Online Access: | https://doi.org/10.1186/s13052-023-01560-2 |
| _version_ | 1797557655604035584 |
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| author | Simone Amendola Isabella Fanizza Sara Scoditti Marta De Rinaldis Antonio Trabacca |
| author_facet | Simone Amendola Isabella Fanizza Sara Scoditti Marta De Rinaldis Antonio Trabacca |
| author_sort | Simone Amendola |
| collection | DOAJ |
| description | Abstract Background The present study analysed data on children and adolescents with a diagnosis of attention-deficit/hyperactivity disorder (ADHD) who were referred to the ADHD reference centre of Scientific Institute IRCCS E. Medea (Brindisi, Italy) for ADHD pharmacotherapy initiation and monitoring overtime. The main aim of the study was to examine differences in pharmacological treatment status (i.e., treatment continuation vs discontinuation) between patients. Methods Seventy-seven children and adolescents (mean age at pharmacotherapy initiation = 9.5, standard deviation = 2.6) with ADHD received drugs treatment for ADHD at the reference center between January, 2013 and May, 2022. Demographic and clinical data were obtained from the Italian Registry for ADHD and medical records. Child Behavior Checklist (CBCL) available data were used. Results Pharmacological treatment status was examined for patients (n = 63) with at least 12 months of follow-up after the first pharmacological treatment for ADHD. After starting pharmacotherapy treatment, 77.8% (n = 49) patients were still on treatment whereas 22.2% (n = 14) discontinued it. No between group difference were observed in demographic and clinical data except for the intelligence quotient/intellectual disability and rule-breaking behavior (n = 40). Conclusions This study stressed the need of periodical assessments, monitoring difficulties with treatment and/or reasons for poor treatment compliance to provide individualized care. |
| first_indexed | 2024-03-10T17:19:42Z |
| format | Article |
| id | doaj.art-dd386014d5914cb0b4d43fbadab1d1cc |
| institution | Directory Open Access Journal |
| issn | 1824-7288 |
| language | English |
| last_indexed | 2024-03-10T17:19:42Z |
| publishDate | 2023-11-01 |
| publisher | BMC |
| record_format | Article |
| series | Italian Journal of Pediatrics |
| spelling | doaj.art-dd386014d5914cb0b4d43fbadab1d1cc2023-11-20T10:23:52ZengBMCItalian Journal of Pediatrics1824-72882023-11-014911910.1186/s13052-023-01560-2Factors associated with pharmacological treatment in children with attention-deficit/hyperactivity disorders: a retrospective study of a series of 77 cases in a single third-level reference Centre in Apulia regionSimone Amendola0Isabella Fanizza1Sara Scoditti2Marta De Rinaldis3Antonio Trabacca4Scientific Institute I.R.C.C.S. “E. Medea”- Unit for Severe Disabilities in Developmental Age and Young Adults (Developmental Neurology and Neurorehabilitation) - Piazza “A. Di Summa”Scientific Institute I.R.C.C.S. “E. Medea”- Unit for Severe Disabilities in Developmental Age and Young Adults (Developmental Neurology and Neurorehabilitation) - Piazza “A. Di Summa”Scientific Institute I.R.C.C.S. “E. Medea”- Unit for Severe Disabilities in Developmental Age and Young Adults (Developmental Neurology and Neurorehabilitation) - Piazza “A. Di Summa”Scientific Institute I.R.C.C.S. “E. Medea”- Unit for Severe Disabilities in Developmental Age and Young Adults (Developmental Neurology and Neurorehabilitation) - Piazza “A. Di Summa”Scientific Institute I.R.C.C.S. “E. Medea”- Unit for Severe Disabilities in Developmental Age and Young Adults (Developmental Neurology and Neurorehabilitation) - Piazza “A. Di Summa”Abstract Background The present study analysed data on children and adolescents with a diagnosis of attention-deficit/hyperactivity disorder (ADHD) who were referred to the ADHD reference centre of Scientific Institute IRCCS E. Medea (Brindisi, Italy) for ADHD pharmacotherapy initiation and monitoring overtime. The main aim of the study was to examine differences in pharmacological treatment status (i.e., treatment continuation vs discontinuation) between patients. Methods Seventy-seven children and adolescents (mean age at pharmacotherapy initiation = 9.5, standard deviation = 2.6) with ADHD received drugs treatment for ADHD at the reference center between January, 2013 and May, 2022. Demographic and clinical data were obtained from the Italian Registry for ADHD and medical records. Child Behavior Checklist (CBCL) available data were used. Results Pharmacological treatment status was examined for patients (n = 63) with at least 12 months of follow-up after the first pharmacological treatment for ADHD. After starting pharmacotherapy treatment, 77.8% (n = 49) patients were still on treatment whereas 22.2% (n = 14) discontinued it. No between group difference were observed in demographic and clinical data except for the intelligence quotient/intellectual disability and rule-breaking behavior (n = 40). Conclusions This study stressed the need of periodical assessments, monitoring difficulties with treatment and/or reasons for poor treatment compliance to provide individualized care.https://doi.org/10.1186/s13052-023-01560-2PsychopharmacologyMedicationDrug prescriptionAdherenceTreatment persistenceDiscontinuation |
| spellingShingle | Simone Amendola Isabella Fanizza Sara Scoditti Marta De Rinaldis Antonio Trabacca Factors associated with pharmacological treatment in children with attention-deficit/hyperactivity disorders: a retrospective study of a series of 77 cases in a single third-level reference Centre in Apulia region Italian Journal of Pediatrics Psychopharmacology Medication Drug prescription Adherence Treatment persistence Discontinuation |
| title | Factors associated with pharmacological treatment in children with attention-deficit/hyperactivity disorders: a retrospective study of a series of 77 cases in a single third-level reference Centre in Apulia region |
| title_full | Factors associated with pharmacological treatment in children with attention-deficit/hyperactivity disorders: a retrospective study of a series of 77 cases in a single third-level reference Centre in Apulia region |
| title_fullStr | Factors associated with pharmacological treatment in children with attention-deficit/hyperactivity disorders: a retrospective study of a series of 77 cases in a single third-level reference Centre in Apulia region |
| title_full_unstemmed | Factors associated with pharmacological treatment in children with attention-deficit/hyperactivity disorders: a retrospective study of a series of 77 cases in a single third-level reference Centre in Apulia region |
| title_short | Factors associated with pharmacological treatment in children with attention-deficit/hyperactivity disorders: a retrospective study of a series of 77 cases in a single third-level reference Centre in Apulia region |
| title_sort | factors associated with pharmacological treatment in children with attention deficit hyperactivity disorders a retrospective study of a series of 77 cases in a single third level reference centre in apulia region |
| topic | Psychopharmacology Medication Drug prescription Adherence Treatment persistence Discontinuation |
| url | https://doi.org/10.1186/s13052-023-01560-2 |
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