β-Cell Replacement Strategies: The Increasing Need for a “β-Cell Dogma”

β-Cell Replacement Strategies: The Increasing Need for a “β-Cell Dogma”

Type 1 diabetes is an auto-immune disease resulting in the loss of pancreatic β-cells and, consequently, in chronic hyperglycemia. Insulin supplementation allows diabetic patients to control their glycaemia quite efficiently, but treated patients still display an overall shortened life expectancy an...

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Bibliographic Details
Main Authors: Andhira Vieira, Noémie Druelle, Fabio Avolio, Tiziana Napolitano, Sergi Navarro-Sanz, Serena Silvano, Patrick Collombat
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-06-01
Series:Frontiers in Genetics
Subjects:
β-cells
differentiation
stem cells
type 1 diabetes
β-cell markers
Online Access:http://journal.frontiersin.org/article/10.3389/fgene.2017.00075/full

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