Biocompatible Polymer for Self-Humidification

Lung supportive devices (LSDs) have been extensively utilized in treating patients diagnosed with various respiratory disorders. However, these devices can cause moisture depletion in the upper airway by interfering with the natural lubrication and air conditioning process. To remedy this, current t...

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Main Authors: Ahmed M. Al-Jumaily, Sandra Grau-Bartual, Nimesha T. Weerasinghe
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Polymers
Subjects:
Online Access:https://www.mdpi.com/2073-4360/15/20/4101
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author Ahmed M. Al-Jumaily
Sandra Grau-Bartual
Nimesha T. Weerasinghe
author_facet Ahmed M. Al-Jumaily
Sandra Grau-Bartual
Nimesha T. Weerasinghe
author_sort Ahmed M. Al-Jumaily
collection DOAJ
description Lung supportive devices (LSDs) have been extensively utilized in treating patients diagnosed with various respiratory disorders. However, these devices can cause moisture depletion in the upper airway by interfering with the natural lubrication and air conditioning process. To remedy this, current technologies implement heated humidification processes, which are bulky, costly, and nonfriendly. However, it has been demonstrated that in a breath cycle, the amount of water vapor in the exhaled air is of a similar quantity to the amount needed to humidify the inhaled air. This research proposes to trap the moisture from exhaled air and reuse it during inhalation by developing a state-of-the-art hydrophilic/hydrophobic polymer tuned to deliver this purpose. Using the atom transfer radical polymerization (ATRP) method, a substrate was successfully created by incorporating poly (N-isopropyl acrylamide) (PNIPAM) onto cotton. The fabricated material exhibited a water vapor release rate of 24.2 ± 1.054%/min at 32 °C, indicating its ability to humidify the inhaled air effectively. These findings highlight the potential of the developed material as a promising solution for applications requiring rapid moisture recovery.
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spelling doaj.art-dd3abcb881cd417ebfde3c24435f79312023-11-19T17:51:10ZengMDPI AGPolymers2073-43602023-10-011520410110.3390/polym15204101Biocompatible Polymer for Self-HumidificationAhmed M. Al-Jumaily0Sandra Grau-Bartual1Nimesha T. Weerasinghe2AUT—Institute of Biomedical Technologies, Auckland University of Technology, Auckland 1010, New ZealandAUT—Institute of Biomedical Technologies, Auckland University of Technology, Auckland 1010, New ZealandAUT—Institute of Biomedical Technologies, Auckland University of Technology, Auckland 1010, New ZealandLung supportive devices (LSDs) have been extensively utilized in treating patients diagnosed with various respiratory disorders. However, these devices can cause moisture depletion in the upper airway by interfering with the natural lubrication and air conditioning process. To remedy this, current technologies implement heated humidification processes, which are bulky, costly, and nonfriendly. However, it has been demonstrated that in a breath cycle, the amount of water vapor in the exhaled air is of a similar quantity to the amount needed to humidify the inhaled air. This research proposes to trap the moisture from exhaled air and reuse it during inhalation by developing a state-of-the-art hydrophilic/hydrophobic polymer tuned to deliver this purpose. Using the atom transfer radical polymerization (ATRP) method, a substrate was successfully created by incorporating poly (N-isopropyl acrylamide) (PNIPAM) onto cotton. The fabricated material exhibited a water vapor release rate of 24.2 ± 1.054%/min at 32 °C, indicating its ability to humidify the inhaled air effectively. These findings highlight the potential of the developed material as a promising solution for applications requiring rapid moisture recovery.https://www.mdpi.com/2073-4360/15/20/4101hydrophilichydrophobichumidificationLCSTCPAP
spellingShingle Ahmed M. Al-Jumaily
Sandra Grau-Bartual
Nimesha T. Weerasinghe
Biocompatible Polymer for Self-Humidification
Polymers
hydrophilic
hydrophobic
humidification
LCST
CPAP
title Biocompatible Polymer for Self-Humidification
title_full Biocompatible Polymer for Self-Humidification
title_fullStr Biocompatible Polymer for Self-Humidification
title_full_unstemmed Biocompatible Polymer for Self-Humidification
title_short Biocompatible Polymer for Self-Humidification
title_sort biocompatible polymer for self humidification
topic hydrophilic
hydrophobic
humidification
LCST
CPAP
url https://www.mdpi.com/2073-4360/15/20/4101
work_keys_str_mv AT ahmedmaljumaily biocompatiblepolymerforselfhumidification
AT sandragraubartual biocompatiblepolymerforselfhumidification
AT nimeshatweerasinghe biocompatiblepolymerforselfhumidification