Development of the rat telencephalon-volumetric analysis
With regard to intensive morphometric changes, morphometry as a method is mainly used for histogenetic studies of brain development in normal and experimental conditions. The aim of our study was to quantitatively analyse morphological parameters of the rat telencephalon during embryonic developmen...
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| Format: | Article |
| Language: | English |
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Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina
2004-08-01
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| Series: | Biomolecules & Biomedicine |
| Subjects: | |
| Online Access: | https://www.bjbms.org/ojs/index.php/bjbms/article/view/3375 |
| _version_ | 1797260784143695872 |
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| author | Selma Aličelebić Đurđica Grbeša |
| author_facet | Selma Aličelebić Đurđica Grbeša |
| author_sort | Selma Aličelebić |
| collection | DOAJ |
| description |
With regard to intensive morphometric changes, morphometry as a method is mainly used for histogenetic studies of brain development in normal and experimental conditions. The aim of our study was to quantitatively analyse morphological parameters of the rat telencephalon during embryonic development. The investigation was carried out on semithin serial sections of rat brain from embryonic days 12 to 15. The volume densities (VV) of the lateral ventricles, the telencephalic neuroepithelium and the surrounding mesenchyme have been analysed stereologically and compared in examined embryonic stages. The neuroepithelial volume density was the smallest (28%) at E13 and the biggest (44%) at E15 (p<0.0005). The mesenchymal volume density was the smallest (32%) at E13 and the biggest (48%) at E14 (p<0.0005). The volume density of lateral ventricles was the biggest (40%) at E13 and the smallest (14%) at E15 (p<0.0005). Neurostereological methods have been making a very valuable contribution to neuroscience over recent years. We have used unbiased stereological counting methods to obtain objective quantitative parameters which show relations between some parts of rat embryonic telencephalon examined during its normal development.
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| first_indexed | 2024-04-24T23:30:49Z |
| format | Article |
| id | doaj.art-dd416de4202d42cf95946dff54d98837 |
| institution | Directory Open Access Journal |
| issn | 2831-0896 2831-090X |
| language | English |
| last_indexed | 2024-04-24T23:30:49Z |
| publishDate | 2004-08-01 |
| publisher | Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina |
| record_format | Article |
| series | Biomolecules & Biomedicine |
| spelling | doaj.art-dd416de4202d42cf95946dff54d988372024-03-15T14:43:56ZengAssociation of Basic Medical Sciences of Federation of Bosnia and HerzegovinaBiomolecules & Biomedicine2831-08962831-090X2004-08-014310.17305/bjbms.2004.3375820Development of the rat telencephalon-volumetric analysisSelma Aličelebić0Đurđica Grbeša1Institute of Histology and Embryology School of Medicine, University of SarajevoDepartment of Histology and Embryology, School of Medicine, University of Zagreb With regard to intensive morphometric changes, morphometry as a method is mainly used for histogenetic studies of brain development in normal and experimental conditions. The aim of our study was to quantitatively analyse morphological parameters of the rat telencephalon during embryonic development. The investigation was carried out on semithin serial sections of rat brain from embryonic days 12 to 15. The volume densities (VV) of the lateral ventricles, the telencephalic neuroepithelium and the surrounding mesenchyme have been analysed stereologically and compared in examined embryonic stages. The neuroepithelial volume density was the smallest (28%) at E13 and the biggest (44%) at E15 (p<0.0005). The mesenchymal volume density was the smallest (32%) at E13 and the biggest (48%) at E14 (p<0.0005). The volume density of lateral ventricles was the biggest (40%) at E13 and the smallest (14%) at E15 (p<0.0005). Neurostereological methods have been making a very valuable contribution to neuroscience over recent years. We have used unbiased stereological counting methods to obtain objective quantitative parameters which show relations between some parts of rat embryonic telencephalon examined during its normal development. https://www.bjbms.org/ojs/index.php/bjbms/article/view/3375rat telencephalondevelopmentstereology |
| spellingShingle | Selma Aličelebić Đurđica Grbeša Development of the rat telencephalon-volumetric analysis Biomolecules & Biomedicine rat telencephalon development stereology |
| title | Development of the rat telencephalon-volumetric analysis |
| title_full | Development of the rat telencephalon-volumetric analysis |
| title_fullStr | Development of the rat telencephalon-volumetric analysis |
| title_full_unstemmed | Development of the rat telencephalon-volumetric analysis |
| title_short | Development of the rat telencephalon-volumetric analysis |
| title_sort | development of the rat telencephalon volumetric analysis |
| topic | rat telencephalon development stereology |
| url | https://www.bjbms.org/ojs/index.php/bjbms/article/view/3375 |
| work_keys_str_mv | AT selmaalicelebic developmentoftherattelencephalonvolumetricanalysis AT đurđicagrbesa developmentoftherattelencephalonvolumetricanalysis |