Prognostic Determinants of Anterior Large Vessel Occlusion in Acute Stroke in Elderly Patients
This study investigated prognostic factors in elderly patients (80 years and older) undergoing mechanical thrombectomy (MT) for anterior circulation large vessel occlusion (LVO) in acute stroke treatment. Of 59 cases, 47.5% achieved a favorable outcome (mRS ≤ 3) at three months, with a mortality rat...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-01-01
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| Series: | Geriatrics |
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| Online Access: | https://www.mdpi.com/2308-3417/9/1/13 |
| _version_ | 1797298175803916288 |
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| author | Takashi Mitsuhashi Kohsuke Teranishi Joji Tokugawa Takumi Mitsuhashi Makoto Hishii Hidenori Oishi |
| author_facet | Takashi Mitsuhashi Kohsuke Teranishi Joji Tokugawa Takumi Mitsuhashi Makoto Hishii Hidenori Oishi |
| author_sort | Takashi Mitsuhashi |
| collection | DOAJ |
| description | This study investigated prognostic factors in elderly patients (80 years and older) undergoing mechanical thrombectomy (MT) for anterior circulation large vessel occlusion (LVO) in acute stroke treatment. Of 59 cases, 47.5% achieved a favorable outcome (mRS ≤ 3) at three months, with a mortality rate of 20.3%. Factors associated with better outcomes included younger age, lower admission National Institute of Health Stroke Scale (NIHSS) scores, lower N-terminal pro-brain natriuretic peptide (NT-proBNP) and D-dimer levels, the presence of the first pass effect (FPE), and successful recanalization. However, logistic regression showed that only lower admission NIHSS scores were significantly correlated with favorable outcomes. In addition, this study suggests that lower admission NT-proBNP and D-dimer levels could potentially serve as prognostic indicators for elderly LVO patients undergoing MT. |
| first_indexed | 2024-03-07T22:31:04Z |
| format | Article |
| id | doaj.art-dd447c574bf74759a8b9dc9ed158d25e |
| institution | Directory Open Access Journal |
| issn | 2308-3417 |
| language | English |
| last_indexed | 2024-03-07T22:31:04Z |
| publishDate | 2024-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Geriatrics |
| spelling | doaj.art-dd447c574bf74759a8b9dc9ed158d25e2024-02-23T15:18:08ZengMDPI AGGeriatrics2308-34172024-01-01911310.3390/geriatrics9010013Prognostic Determinants of Anterior Large Vessel Occlusion in Acute Stroke in Elderly PatientsTakashi Mitsuhashi0Kohsuke Teranishi1Joji Tokugawa2Takumi Mitsuhashi3Makoto Hishii4Hidenori Oishi5Department of Neurosurgery, Juntendo University Nerima Hospital, Tokyo 177-8521, JapanDepartment of Neurosurgery and Neuroendovascular Therapy, Juntendo University School of Medicine, Tokyo 113-8421, JapanDepartment of Neurosurgery, Juntendo University Nerima Hospital, Tokyo 177-8521, JapanDepartment of Neurosurgery, Juntendo University Nerima Hospital, Tokyo 177-8521, JapanDepartment of Neurosurgery, Juntendo University Nerima Hospital, Tokyo 177-8521, JapanDepartment of Neurosurgery and Neuroendovascular Therapy, Juntendo University School of Medicine, Tokyo 113-8421, JapanThis study investigated prognostic factors in elderly patients (80 years and older) undergoing mechanical thrombectomy (MT) for anterior circulation large vessel occlusion (LVO) in acute stroke treatment. Of 59 cases, 47.5% achieved a favorable outcome (mRS ≤ 3) at three months, with a mortality rate of 20.3%. Factors associated with better outcomes included younger age, lower admission National Institute of Health Stroke Scale (NIHSS) scores, lower N-terminal pro-brain natriuretic peptide (NT-proBNP) and D-dimer levels, the presence of the first pass effect (FPE), and successful recanalization. However, logistic regression showed that only lower admission NIHSS scores were significantly correlated with favorable outcomes. In addition, this study suggests that lower admission NT-proBNP and D-dimer levels could potentially serve as prognostic indicators for elderly LVO patients undergoing MT.https://www.mdpi.com/2308-3417/9/1/13mechanical thrombectomylarge vessel occlusionelderlyprognosis |
| spellingShingle | Takashi Mitsuhashi Kohsuke Teranishi Joji Tokugawa Takumi Mitsuhashi Makoto Hishii Hidenori Oishi Prognostic Determinants of Anterior Large Vessel Occlusion in Acute Stroke in Elderly Patients Geriatrics mechanical thrombectomy large vessel occlusion elderly prognosis |
| title | Prognostic Determinants of Anterior Large Vessel Occlusion in Acute Stroke in Elderly Patients |
| title_full | Prognostic Determinants of Anterior Large Vessel Occlusion in Acute Stroke in Elderly Patients |
| title_fullStr | Prognostic Determinants of Anterior Large Vessel Occlusion in Acute Stroke in Elderly Patients |
| title_full_unstemmed | Prognostic Determinants of Anterior Large Vessel Occlusion in Acute Stroke in Elderly Patients |
| title_short | Prognostic Determinants of Anterior Large Vessel Occlusion in Acute Stroke in Elderly Patients |
| title_sort | prognostic determinants of anterior large vessel occlusion in acute stroke in elderly patients |
| topic | mechanical thrombectomy large vessel occlusion elderly prognosis |
| url | https://www.mdpi.com/2308-3417/9/1/13 |
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