Coexistence of spondyloarthritis and joint hypermobility syndrome: rare or unknown association?

We report two cases of siblings presenting coexisting non-radiographic axial spondyloartrhritis and joint hypermobility syndrome, complaining of back pain with morning stiffness, enthesitis, peripheral arthralgia, high erythrocyte sedimentation rate and C-reactive protein level and positive HLA-B27....

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Main Authors: J.B. Pinto Carneiro, T. Pinto de Souza, T.M.L. Antunes de Oliveira, S.L. Euzébio Ribeiro
Format: Article
Language:English
Published: PAGEPress Publications 2017-09-01
Series:Reumatismo
Subjects:
Online Access:http://www.reumatismo.org/index.php/reuma/article/view/993
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author J.B. Pinto Carneiro
T. Pinto de Souza
T.M.L. Antunes de Oliveira
S.L. Euzébio Ribeiro
author_facet J.B. Pinto Carneiro
T. Pinto de Souza
T.M.L. Antunes de Oliveira
S.L. Euzébio Ribeiro
author_sort J.B. Pinto Carneiro
collection DOAJ
description We report two cases of siblings presenting coexisting non-radiographic axial spondyloartrhritis and joint hypermobility syndrome, complaining of back pain with morning stiffness, enthesitis, peripheral arthralgia, high erythrocyte sedimentation rate and C-reactive protein level and positive HLA-B27. The association of these two conditions is rare, but especially interesting in view of their contrasting features, one causing axial skeleton stiffness, the other a wider range of peripheral joint movements. Coexistence of these two opposite disorders causes confusion in diagnosis and management, resulting in lower quality of life for patients, as they are in pain from the early stages. Therefore, this association is suspected in young individuals with back pain and physical exam findings of peripheral joint hypermobility and axial skeleton loss of mobility.
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spelling doaj.art-dd447ff0ea4645ce899dd004d685cfc22022-12-22T02:07:39ZengPAGEPress PublicationsReumatismo0048-74492240-26832017-09-0169312613010.4081/reumatismo.2017.993753Coexistence of spondyloarthritis and joint hypermobility syndrome: rare or unknown association?J.B. Pinto Carneiro0T. Pinto de Souza1T.M.L. Antunes de Oliveira2S.L. Euzébio Ribeiro3Rheumatology Section, University Hospital Getúlio Vargas/Federal University of AmazonasRheumatology Section, University Hospital Getúlio Vargas/Federal University of AmazonasRegional Hospital of Taguatinga, Federal DistrictRheumatology Department, Federal University of AmazonasWe report two cases of siblings presenting coexisting non-radiographic axial spondyloartrhritis and joint hypermobility syndrome, complaining of back pain with morning stiffness, enthesitis, peripheral arthralgia, high erythrocyte sedimentation rate and C-reactive protein level and positive HLA-B27. The association of these two conditions is rare, but especially interesting in view of their contrasting features, one causing axial skeleton stiffness, the other a wider range of peripheral joint movements. Coexistence of these two opposite disorders causes confusion in diagnosis and management, resulting in lower quality of life for patients, as they are in pain from the early stages. Therefore, this association is suspected in young individuals with back pain and physical exam findings of peripheral joint hypermobility and axial skeleton loss of mobility.http://www.reumatismo.org/index.php/reuma/article/view/993Non-radiographic axial spondyloarthritisSpondyloarthritisHLA-B27HypermobilityJoint hypermobility syndrome.
spellingShingle J.B. Pinto Carneiro
T. Pinto de Souza
T.M.L. Antunes de Oliveira
S.L. Euzébio Ribeiro
Coexistence of spondyloarthritis and joint hypermobility syndrome: rare or unknown association?
Reumatismo
Non-radiographic axial spondyloarthritis
Spondyloarthritis
HLA-B27
Hypermobility
Joint hypermobility syndrome.
title Coexistence of spondyloarthritis and joint hypermobility syndrome: rare or unknown association?
title_full Coexistence of spondyloarthritis and joint hypermobility syndrome: rare or unknown association?
title_fullStr Coexistence of spondyloarthritis and joint hypermobility syndrome: rare or unknown association?
title_full_unstemmed Coexistence of spondyloarthritis and joint hypermobility syndrome: rare or unknown association?
title_short Coexistence of spondyloarthritis and joint hypermobility syndrome: rare or unknown association?
title_sort coexistence of spondyloarthritis and joint hypermobility syndrome rare or unknown association
topic Non-radiographic axial spondyloarthritis
Spondyloarthritis
HLA-B27
Hypermobility
Joint hypermobility syndrome.
url http://www.reumatismo.org/index.php/reuma/article/view/993
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