Comparative transcriptional profiling of the early host response to infection by typhoidal and non-typhoidal Salmonella serovars in human intestinal organoids.

Comparative transcriptional profiling of the early host response to infection by typhoidal and non-typhoidal Salmonella serovars in human intestinal organoids.

Salmonella enterica represents over 2500 serovars associated with a wide-ranging spectrum of disease; from self-limiting gastroenteritis to invasive infections caused by non-typhoidal serovars (NTS) and typhoidal serovars, respectively. Host factors strongly influence infection outcome as malnourish...

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Main Authors: Basel H Abuaita, Anna-Lisa E Lawrence, Ryan P Berger, David R Hill, Sha Huang, Veda K Yadagiri, Brooke Bons, Courtney Fields, Christiane E Wobus, Jason R Spence, Vincent B Young, Mary X O'Riordan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-10-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1009987

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