Antioxidant Fusion Protein SOD1-Tat Increases the Engraftment Efficiency of Total Bone Marrow Cells in Irradiated Mice

Antioxidant Fusion Protein SOD1-Tat Increases the Engraftment Efficiency of Total Bone Marrow Cells in Irradiated Mice

Total body irradiation is a standard procedure of bone marrow transplantation (BMT) which causes a rapid increase in reactive oxygen species (ROS) in the bone marrow microenvironment during BMT. The increase in ROS reduces the engraftment ability of donor cells, thereby affecting the bone marrow rec...

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Bibliographic Details
Main Authors: Ting Bei, Xusong Cao, Yun Liu, Jinmei Li, Haihua Luo, Lin Huang, Tian Tian, Lei Li, Yong Jiang
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Molecules
Subjects:
cells penetrating peptides
bone marrow transplantation
reactive oxygen species
engraftment
superoxide dismutase
Online Access:https://www.mdpi.com/1420-3049/26/11/3395

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