Evidence that Ergosterol Biosynthesis Modulates Activity of the Pdr1 Transcription Factor in <named-content content-type="genus-species">Candida glabrata</named-content>

ABSTRACT A crucial limitation in antifungal chemotherapy is the limited number of antifungal drugs currently available. Azole drugs represent the most commonly used chemotherapeutic, and loss of efficacy of these drugs is a major risk factor in successful treatment of a variety of fungal diseases. C...

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Bibliographic Details
Main Authors: Bao Gia Vu, Grace Heredge Thomas, W. Scott Moye-Rowley
Format: Article
Language:English
Published: American Society for Microbiology 2019-06-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mBio.00934-19