How gene expression profiles disclose vital processes and immune responses in Mytilus spp.
ISJ 8: 179-189, 2011 ISSN 1824-307XREVIEWGene expression studies largely support the understanding of gene-environment interactions in humans and other living organisms but the lack of genomic and genetic information often complicates the analysis of functional responses in non-traditional model spe...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
University of Modena and Reggio Emilia
2011-09-01
|
| Series: | Invertebrate Survival Journal |
| Subjects: | |
| Online Access: | http://www.isj.unimo.it/articoli/ISJ245.pdf |
| _version_ | 1818203543838916608 |
|---|---|
| author | S Domeneghetti C Manfrin L Varotto U Rosani M Gerdol G De Moro A Pallavicini P Venier |
| author_facet | S Domeneghetti C Manfrin L Varotto U Rosani M Gerdol G De Moro A Pallavicini P Venier |
| author_sort | S Domeneghetti |
| collection | DOAJ |
| description | ISJ 8: 179-189, 2011 ISSN 1824-307XREVIEWGene expression studies largely support the understanding of gene-environment interactions in humans and other living organisms but the lack of genomic and genetic information often complicates the analysis of functional responses in non-traditional model species. Nevertheless, the fast advancement of DNA microarray and sequencing technologies now makes global gene expression analysis possible in virtually any species of interest. As regards the Mytilus genus, tens of thousands Expressed Sequence Tags (ESTs) are currently available for M. californianus and M. galloprovincialis, and DNA microarrays have been developed. Among them, Immunochip 1.0 specifically includes 1,820 probes of genes centrally involved or modulated in the innate immune responses of the Mediterranean mussel. This review recalls peculiarities and applications of the existing mussel DNA microarrays and finally summarizes facts concerning a variety of transcript sequences likely involved in the mussel immunity. Beside DNA microarrays, Next Generation Sequencing (NGS) technologies now offer new and broader research perspectives, from the whole transcriptome coverage to the Mytilus genome sequencing. |
| first_indexed | 2024-12-12T03:27:01Z |
| format | Article |
| id | doaj.art-dd4d92c7614e4770a82a4cb67dcfc487 |
| institution | Directory Open Access Journal |
| issn | 1824-307X |
| language | English |
| last_indexed | 2024-12-12T03:27:01Z |
| publishDate | 2011-09-01 |
| publisher | University of Modena and Reggio Emilia |
| record_format | Article |
| series | Invertebrate Survival Journal |
| spelling | doaj.art-dd4d92c7614e4770a82a4cb67dcfc4872022-12-22T00:40:00ZengUniversity of Modena and Reggio EmiliaInvertebrate Survival Journal1824-307X2011-09-0182179189How gene expression profiles disclose vital processes and immune responses in Mytilus spp.S DomeneghettiC ManfrinL VarottoU RosaniM GerdolG De MoroA PallaviciniP VenierISJ 8: 179-189, 2011 ISSN 1824-307XREVIEWGene expression studies largely support the understanding of gene-environment interactions in humans and other living organisms but the lack of genomic and genetic information often complicates the analysis of functional responses in non-traditional model species. Nevertheless, the fast advancement of DNA microarray and sequencing technologies now makes global gene expression analysis possible in virtually any species of interest. As regards the Mytilus genus, tens of thousands Expressed Sequence Tags (ESTs) are currently available for M. californianus and M. galloprovincialis, and DNA microarrays have been developed. Among them, Immunochip 1.0 specifically includes 1,820 probes of genes centrally involved or modulated in the innate immune responses of the Mediterranean mussel. This review recalls peculiarities and applications of the existing mussel DNA microarrays and finally summarizes facts concerning a variety of transcript sequences likely involved in the mussel immunity. Beside DNA microarrays, Next Generation Sequencing (NGS) technologies now offer new and broader research perspectives, from the whole transcriptome coverage to the Mytilus genome sequencing.http://www.isj.unimo.it/articoli/ISJ245.pdfMytilusDNA microarrayinnate immunityESTsantimicrobial peptidesC1q |
| spellingShingle | S Domeneghetti C Manfrin L Varotto U Rosani M Gerdol G De Moro A Pallavicini P Venier How gene expression profiles disclose vital processes and immune responses in Mytilus spp. Invertebrate Survival Journal Mytilus DNA microarray innate immunity ESTs antimicrobial peptides C1q |
| title | How gene expression profiles disclose vital processes and immune responses in Mytilus spp. |
| title_full | How gene expression profiles disclose vital processes and immune responses in Mytilus spp. |
| title_fullStr | How gene expression profiles disclose vital processes and immune responses in Mytilus spp. |
| title_full_unstemmed | How gene expression profiles disclose vital processes and immune responses in Mytilus spp. |
| title_short | How gene expression profiles disclose vital processes and immune responses in Mytilus spp. |
| title_sort | how gene expression profiles disclose vital processes and immune responses in mytilus spp |
| topic | Mytilus DNA microarray innate immunity ESTs antimicrobial peptides C1q |
| url | http://www.isj.unimo.it/articoli/ISJ245.pdf |
| work_keys_str_mv | AT sdomeneghetti howgeneexpressionprofilesdisclosevitalprocessesandimmuneresponsesinmytilusspp AT cmanfrin howgeneexpressionprofilesdisclosevitalprocessesandimmuneresponsesinmytilusspp AT lvarotto howgeneexpressionprofilesdisclosevitalprocessesandimmuneresponsesinmytilusspp AT urosani howgeneexpressionprofilesdisclosevitalprocessesandimmuneresponsesinmytilusspp AT mgerdol howgeneexpressionprofilesdisclosevitalprocessesandimmuneresponsesinmytilusspp AT gdemoro howgeneexpressionprofilesdisclosevitalprocessesandimmuneresponsesinmytilusspp AT apallavicini howgeneexpressionprofilesdisclosevitalprocessesandimmuneresponsesinmytilusspp AT pvenier howgeneexpressionprofilesdisclosevitalprocessesandimmuneresponsesinmytilusspp |