Relationship between retinopathy and asymptomatic atherosclerosis determined by measurement of carotid intima-media thickness in patients with type 2 diabetes mellitus
Objective: Presence of diabetic retinopathy (DR) may be used as an early marker of atherosclerosis in type 2 diabetes mellitus (DM) patients. This study aimed to investigate the relationship between the presence of DR and carotid intimamedia thickness (CIMT), which is an indicator of early atherosc...
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| Format: | Article |
| Language: | English |
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KARE Publishing
2016-02-01
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| Series: | Türk Kardiyoloji Derneği Arşivi |
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| Online Access: | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tkd&un=TKDA-69313 |
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| author | İbrahim Kocaoğlu Emine Kocaoğlu Uğur Arslan Mustafa Mücahit Balcı Murat Vural Mehmet Numan Alp Sinan Aydoğdu |
| author_facet | İbrahim Kocaoğlu Emine Kocaoğlu Uğur Arslan Mustafa Mücahit Balcı Murat Vural Mehmet Numan Alp Sinan Aydoğdu |
| author_sort | İbrahim Kocaoğlu |
| collection | DOAJ |
| description | Objective: Presence of diabetic retinopathy (DR) may be used as an early marker of atherosclerosis in type 2 diabetes mellitus (DM) patients. This study aimed to investigate the relationship between the presence of DR and carotid intimamedia thickness (CIMT), which is an indicator of early atherosclerosis in patients with type 2 DM.
Methods: Thirty DM patients with retinopathy (DR group), 28 DM patients without retinopathy (non-DR group), and 27 healthy controls (control group) were included in the study. CIMT was assessed using a high-resolution B-mode ultrasonography device. Results: Mean CIMT was found to be 0.9+-0.17 mm in the DR group, 0.8+-0.16 mm in the non-DR group, and 0.7+-0.13 mm in the control group. CIMT was found to be statistically significantly higher in the DR group compared to the other 2 groups (p<0.001). When multivariate analysis was performed, presence of DR still remained as an independent risk factor for increased CIMT values.
Conclusion: Presence of DR in type 2 DM patients is an independent risk factor in terms of increased CIMT, which is considered to be a finding of subclinical atherosclerosis. Therefore, we believe that type 2 DM patients with retinopathy should be closely followed in terms of cardiovascular events. |
| first_indexed | 2024-04-10T13:59:23Z |
| format | Article |
| id | doaj.art-dd530f03a8e14c68a944e3c84b80af5d |
| institution | Directory Open Access Journal |
| issn | 1016-5169 |
| language | English |
| last_indexed | 2024-04-10T13:59:23Z |
| publishDate | 2016-02-01 |
| publisher | KARE Publishing |
| record_format | Article |
| series | Türk Kardiyoloji Derneği Arşivi |
| spelling | doaj.art-dd530f03a8e14c68a944e3c84b80af5d2023-02-15T16:10:19ZengKARE PublishingTürk Kardiyoloji Derneği Arşivi1016-51692016-02-01441242910.5543/tkda.2015.69313TKDA-69313Relationship between retinopathy and asymptomatic atherosclerosis determined by measurement of carotid intima-media thickness in patients with type 2 diabetes mellitusİbrahim Kocaoğlu0Emine Kocaoğlu1Uğur Arslan2Mustafa Mücahit Balcı3Murat Vural4Mehmet Numan Alp5Sinan Aydoğdu6Aydın State Hospital, Department Of Cardiology, Aydin - TurkeyAydın State Hospital, Department Of Ophthalmology, Aydin - TurkeySamsun Education And Research Hospital, Department Of Cardiology, Samsun - TurkeyTurkiye Yuksek Ihtisas Education And Research Hospital, Department Of Cardiology, Ankara - TurkeyAnkara Numune Education And Research Hospital, Department Of Radiology, Ankara - TurkeyAnkara Numune Education And Research Hospital, Department Of Radiology, Ankara - TurkeyTurkiye Yuksek Ihtisas Education And Research Hospital, Department Of Cardiology, Ankara - TurkeyObjective: Presence of diabetic retinopathy (DR) may be used as an early marker of atherosclerosis in type 2 diabetes mellitus (DM) patients. This study aimed to investigate the relationship between the presence of DR and carotid intimamedia thickness (CIMT), which is an indicator of early atherosclerosis in patients with type 2 DM. Methods: Thirty DM patients with retinopathy (DR group), 28 DM patients without retinopathy (non-DR group), and 27 healthy controls (control group) were included in the study. CIMT was assessed using a high-resolution B-mode ultrasonography device. Results: Mean CIMT was found to be 0.9+-0.17 mm in the DR group, 0.8+-0.16 mm in the non-DR group, and 0.7+-0.13 mm in the control group. CIMT was found to be statistically significantly higher in the DR group compared to the other 2 groups (p<0.001). When multivariate analysis was performed, presence of DR still remained as an independent risk factor for increased CIMT values. Conclusion: Presence of DR in type 2 DM patients is an independent risk factor in terms of increased CIMT, which is considered to be a finding of subclinical atherosclerosis. Therefore, we believe that type 2 DM patients with retinopathy should be closely followed in terms of cardiovascular events.https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tkd&un=TKDA-69313atherosclerosiscarotid intima media thickness; diabetes mellitus; retinopathy. |
| spellingShingle | İbrahim Kocaoğlu Emine Kocaoğlu Uğur Arslan Mustafa Mücahit Balcı Murat Vural Mehmet Numan Alp Sinan Aydoğdu Relationship between retinopathy and asymptomatic atherosclerosis determined by measurement of carotid intima-media thickness in patients with type 2 diabetes mellitus Türk Kardiyoloji Derneği Arşivi atherosclerosis carotid intima media thickness; diabetes mellitus; retinopathy. |
| title | Relationship between retinopathy and asymptomatic atherosclerosis determined by measurement of carotid intima-media thickness in patients with type 2 diabetes mellitus |
| title_full | Relationship between retinopathy and asymptomatic atherosclerosis determined by measurement of carotid intima-media thickness in patients with type 2 diabetes mellitus |
| title_fullStr | Relationship between retinopathy and asymptomatic atherosclerosis determined by measurement of carotid intima-media thickness in patients with type 2 diabetes mellitus |
| title_full_unstemmed | Relationship between retinopathy and asymptomatic atherosclerosis determined by measurement of carotid intima-media thickness in patients with type 2 diabetes mellitus |
| title_short | Relationship between retinopathy and asymptomatic atherosclerosis determined by measurement of carotid intima-media thickness in patients with type 2 diabetes mellitus |
| title_sort | relationship between retinopathy and asymptomatic atherosclerosis determined by measurement of carotid intima media thickness in patients with type 2 diabetes mellitus |
| topic | atherosclerosis carotid intima media thickness; diabetes mellitus; retinopathy. |
| url | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tkd&un=TKDA-69313 |
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