Study of Cinobufagin as a Promising Anticancer Agent in Uveal Melanoma Through Intrinsic Apoptosis Pathway

Study of Cinobufagin as a Promising Anticancer Agent in Uveal Melanoma Through Intrinsic Apoptosis Pathway

Uveal melanoma (UM) is the most common primary intraocular carcinoma in adults. Cinobufagin, secreted by the Asiatic toad Bufo gargarizans, is a traditional Chinese medicine, widely used in tumor treatment. Here, we explored the potential antitumor function of cinobufagin and investigated its bioche...

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Bibliographic Details
Main Authors: Leilei Zhang, Xiaolin Huang, Tao Guo, Huixue Wang, Haiyan Fan, Li Fang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Oncology
Subjects:
cinobufagin
anticancer agent
uveal melanoma
apoptosis
MMP
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.00325/full

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