Air enema reduction versus hydrostatic enema reduction for intussusceptions in children: A systematic review and meta-analysis.
<h4>Objectives</h4>We conducted a comprehensive meta-analysis to compare the effectiveness and safety of fluoroscopy-guided air enema reduction (FGAR) and ultrasound-guided hydrostatic enema reduction (UGHR) for the treatment of intussusception in pediatric patients.<h4>Methods<...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2024-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0297985 |
| _version_ | 1797238430533419008 |
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| author | Lan Liu Ling Zhang Yifan Fang Yingying Yang Wen You Jianxi Bai Bing Zhang Siqi Xie Yuanyuan Fang |
| author_facet | Lan Liu Ling Zhang Yifan Fang Yingying Yang Wen You Jianxi Bai Bing Zhang Siqi Xie Yuanyuan Fang |
| author_sort | Lan Liu |
| collection | DOAJ |
| description | <h4>Objectives</h4>We conducted a comprehensive meta-analysis to compare the effectiveness and safety of fluoroscopy-guided air enema reduction (FGAR) and ultrasound-guided hydrostatic enema reduction (UGHR) for the treatment of intussusception in pediatric patients.<h4>Methods</h4>A systematic review and meta-analysis were conducted on retrospective studies obtained from various databases, including PUBMED, MEDLINE, Cochrane, Google Scholar, China National Knowledge Infrastructure (CNKI), WanFang, and VIP Database. The search included publications from January 1, 2003, to March 31, 2023, with the last search done on Jan 15, 2023.<h4>Results</h4>We included 49 randomized controlled studies and retrospective cohort studies involving a total of 9,391 patients, with 4,841 in the UGHR and 4,550 in the FGAR. Specifically, UGHR exhibited a significantly shorter time to reduction (WMD = -4.183, 95% CI = (-5.402, -2.964), P < 0.001), a higher rate of successful reduction (RR = 1.128, 95% CI = (1.099, 1.157), P < 0.001), and a reduced length of hospital stay (WMD = -1.215, 95% CI = (-1.58, -0.85), P < 0.001). Furthermore, UGHR repositioning was associated with a diminished overall complication rate (RR = 0.296, 95% CI = (0.225, 0.389), P < 0.001) and a lowered incidence of perforation (RR = 0.405, 95% CI = (0.244, 0.670), P < 0.001).<h4>Conclusion</h4>UGHR offers the benefits of being non-radioactive, achieving a shorter reduction time, demonstrating a higher success rate in repositioning in particular, resulting in a reduced length of postoperative hospital stay, and yielding a lower overall incidence of postoperative complications, including a reduced risk of associated perforations. |
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| format | Article |
| id | doaj.art-dd597bf5f3404076a175222975162694 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-04-24T17:35:31Z |
| publishDate | 2024-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-dd597bf5f3404076a1752229751626942024-03-28T05:34:59ZengPublic Library of Science (PLoS)PLoS ONE1932-62032024-01-01193e029798510.1371/journal.pone.0297985Air enema reduction versus hydrostatic enema reduction for intussusceptions in children: A systematic review and meta-analysis.Lan LiuLing ZhangYifan FangYingying YangWen YouJianxi BaiBing ZhangSiqi XieYuanyuan Fang<h4>Objectives</h4>We conducted a comprehensive meta-analysis to compare the effectiveness and safety of fluoroscopy-guided air enema reduction (FGAR) and ultrasound-guided hydrostatic enema reduction (UGHR) for the treatment of intussusception in pediatric patients.<h4>Methods</h4>A systematic review and meta-analysis were conducted on retrospective studies obtained from various databases, including PUBMED, MEDLINE, Cochrane, Google Scholar, China National Knowledge Infrastructure (CNKI), WanFang, and VIP Database. The search included publications from January 1, 2003, to March 31, 2023, with the last search done on Jan 15, 2023.<h4>Results</h4>We included 49 randomized controlled studies and retrospective cohort studies involving a total of 9,391 patients, with 4,841 in the UGHR and 4,550 in the FGAR. Specifically, UGHR exhibited a significantly shorter time to reduction (WMD = -4.183, 95% CI = (-5.402, -2.964), P < 0.001), a higher rate of successful reduction (RR = 1.128, 95% CI = (1.099, 1.157), P < 0.001), and a reduced length of hospital stay (WMD = -1.215, 95% CI = (-1.58, -0.85), P < 0.001). Furthermore, UGHR repositioning was associated with a diminished overall complication rate (RR = 0.296, 95% CI = (0.225, 0.389), P < 0.001) and a lowered incidence of perforation (RR = 0.405, 95% CI = (0.244, 0.670), P < 0.001).<h4>Conclusion</h4>UGHR offers the benefits of being non-radioactive, achieving a shorter reduction time, demonstrating a higher success rate in repositioning in particular, resulting in a reduced length of postoperative hospital stay, and yielding a lower overall incidence of postoperative complications, including a reduced risk of associated perforations.https://doi.org/10.1371/journal.pone.0297985 |
| spellingShingle | Lan Liu Ling Zhang Yifan Fang Yingying Yang Wen You Jianxi Bai Bing Zhang Siqi Xie Yuanyuan Fang Air enema reduction versus hydrostatic enema reduction for intussusceptions in children: A systematic review and meta-analysis. PLoS ONE |
| title | Air enema reduction versus hydrostatic enema reduction for intussusceptions in children: A systematic review and meta-analysis. |
| title_full | Air enema reduction versus hydrostatic enema reduction for intussusceptions in children: A systematic review and meta-analysis. |
| title_fullStr | Air enema reduction versus hydrostatic enema reduction for intussusceptions in children: A systematic review and meta-analysis. |
| title_full_unstemmed | Air enema reduction versus hydrostatic enema reduction for intussusceptions in children: A systematic review and meta-analysis. |
| title_short | Air enema reduction versus hydrostatic enema reduction for intussusceptions in children: A systematic review and meta-analysis. |
| title_sort | air enema reduction versus hydrostatic enema reduction for intussusceptions in children a systematic review and meta analysis |
| url | https://doi.org/10.1371/journal.pone.0297985 |
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