Severe gut mucosal injury induces profound systemic inflammation and spleen-associated lymphoid organ response

Severe gut mucosal injury induces profound systemic inflammation and spleen-associated lymphoid organ response

Clinical evidence indicates a connection between gut injuries, infections, inflammation, and an increased susceptibility to systemic inflammation. Nevertheless, the animal models designed to replicate this progression are inadequate, and the fundamental mechanisms are still largely unknown. This res...

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Bibliographic Details
Main Authors: Xiao Wang, Chao Du, Saravanan Subramanian, Lucas Turner, Hua Geng, Heng-Fu Bu, Xiao-Di Tan
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Immunology
Subjects:
DSS-model
gut injury
systemic inflammation
spleen dysfunction
lymphoid organ
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1340442/full

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