Optimal annual body mass index change for preventing spontaneous preterm birth in a subsequent pregnancy
Abstract Preterm birth (PTB) is a leading cause of neonatal morbidity and mortality. Although PTB is known to recur, interpregnancy preventive strategies for PTB have not been established to date. Annual BMI change can serve as a specific target value for preventing obstetric complications during in...
| Huvudupphovsmän: | , , , , , , , , , , , , , |
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| Materialtyp: | Artikel |
| Språk: | English |
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Nature Portfolio
2022-10-01
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| Serie: | Scientific Reports |
| Länkar: | https://doi.org/10.1038/s41598-022-22495-4 |
| _version_ | 1828140537619677184 |
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| author | Sho Tano Tomomi Kotani Takafumi Ushida Masato Yoshihara Kenji Imai Tomoko Nakano-Kobayashi Yoshinori Moriyama Yukako Iitani Fumie Kinoshita Shigeru Yoshida Mamoru Yamashita Yasuyuki Kishigami Hidenori Oguchi Hiroaki Kajiyama |
| author_facet | Sho Tano Tomomi Kotani Takafumi Ushida Masato Yoshihara Kenji Imai Tomoko Nakano-Kobayashi Yoshinori Moriyama Yukako Iitani Fumie Kinoshita Shigeru Yoshida Mamoru Yamashita Yasuyuki Kishigami Hidenori Oguchi Hiroaki Kajiyama |
| author_sort | Sho Tano |
| collection | DOAJ |
| description | Abstract Preterm birth (PTB) is a leading cause of neonatal morbidity and mortality. Although PTB is known to recur, interpregnancy preventive strategies for PTB have not been established to date. Annual BMI change can serve as a specific target value for preventing obstetric complications during interpregnancy care/counseling. This value can also account for age-related weight gain (0.2 kg/m2/year). In a multicenter retrospective study, we investigated the optimal annual BMI change for preventing PTB recurrence using the data of individuals who had two singleton births from 2009 to 2019. The association between annual BMI change and spontaneous PTB (sPTB) was analyzed by separating cases of medically indicated PTB (mPTB) from those of sPTB. Previous history of sPTB was strongly associated with sPTB in the subsequent pregnancy (adjusted odds ratio [aOR], 12.7; 95% confidence interval [CI], 6.5–24.8). Increase in annual BMI was negatively associated with sPTB (aOR, 0.6; 95% CI 0.5–0.9). The sPTB recurrence rate was significantly lower in patients with an annual BMI change of ≥ 0.25 kg/m2/year than in those with an annual BMI change of < 0.25 kg/m2/year (7.7% vs. 35.0%, p = 0.011). Our findings suggest that age-related annual BMI gain between pregnancies may help prevent sPTB recurrence. |
| first_indexed | 2024-04-11T19:11:13Z |
| format | Article |
| id | doaj.art-dd5ca66d6c5a45a3a88b51bc892ac789 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-04-11T19:11:13Z |
| publishDate | 2022-10-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-dd5ca66d6c5a45a3a88b51bc892ac7892022-12-22T04:07:37ZengNature PortfolioScientific Reports2045-23222022-10-0112111010.1038/s41598-022-22495-4Optimal annual body mass index change for preventing spontaneous preterm birth in a subsequent pregnancySho Tano0Tomomi Kotani1Takafumi Ushida2Masato Yoshihara3Kenji Imai4Tomoko Nakano-Kobayashi5Yoshinori Moriyama6Yukako Iitani7Fumie Kinoshita8Shigeru Yoshida9Mamoru Yamashita10Yasuyuki Kishigami11Hidenori Oguchi12Hiroaki Kajiyama13Department of Obstetrics and Gynecology, Nagoya University Graduate School of MedicineDepartment of Obstetrics and Gynecology, Nagoya University Graduate School of MedicineDepartment of Obstetrics and Gynecology, Nagoya University Graduate School of MedicineDepartment of Obstetrics and Gynecology, Nagoya University Graduate School of MedicineDepartment of Obstetrics and Gynecology, Nagoya University Graduate School of MedicineDepartment of Obstetrics and Gynecology, Nagoya University Graduate School of MedicineDepartment of Obstetrics and Gynecology, Fujita Health University School of MedicineDepartment of Obstetrics and Gynecology, Nagoya University Graduate School of MedicineData Science Division, Data Coordinating Center, Department of Advanced Medicine, Nagoya University HospitalKishokai Medical CorporationKishokai Medical CorporationDepartment of Obstetrics, Perinatal Medical Center, Toyota Memorial HospitalDepartment of Obstetrics, Perinatal Medical Center, Toyota Memorial HospitalDepartment of Obstetrics and Gynecology, Nagoya University Graduate School of MedicineAbstract Preterm birth (PTB) is a leading cause of neonatal morbidity and mortality. Although PTB is known to recur, interpregnancy preventive strategies for PTB have not been established to date. Annual BMI change can serve as a specific target value for preventing obstetric complications during interpregnancy care/counseling. This value can also account for age-related weight gain (0.2 kg/m2/year). In a multicenter retrospective study, we investigated the optimal annual BMI change for preventing PTB recurrence using the data of individuals who had two singleton births from 2009 to 2019. The association between annual BMI change and spontaneous PTB (sPTB) was analyzed by separating cases of medically indicated PTB (mPTB) from those of sPTB. Previous history of sPTB was strongly associated with sPTB in the subsequent pregnancy (adjusted odds ratio [aOR], 12.7; 95% confidence interval [CI], 6.5–24.8). Increase in annual BMI was negatively associated with sPTB (aOR, 0.6; 95% CI 0.5–0.9). The sPTB recurrence rate was significantly lower in patients with an annual BMI change of ≥ 0.25 kg/m2/year than in those with an annual BMI change of < 0.25 kg/m2/year (7.7% vs. 35.0%, p = 0.011). Our findings suggest that age-related annual BMI gain between pregnancies may help prevent sPTB recurrence.https://doi.org/10.1038/s41598-022-22495-4 |
| spellingShingle | Sho Tano Tomomi Kotani Takafumi Ushida Masato Yoshihara Kenji Imai Tomoko Nakano-Kobayashi Yoshinori Moriyama Yukako Iitani Fumie Kinoshita Shigeru Yoshida Mamoru Yamashita Yasuyuki Kishigami Hidenori Oguchi Hiroaki Kajiyama Optimal annual body mass index change for preventing spontaneous preterm birth in a subsequent pregnancy Scientific Reports |
| title | Optimal annual body mass index change for preventing spontaneous preterm birth in a subsequent pregnancy |
| title_full | Optimal annual body mass index change for preventing spontaneous preterm birth in a subsequent pregnancy |
| title_fullStr | Optimal annual body mass index change for preventing spontaneous preterm birth in a subsequent pregnancy |
| title_full_unstemmed | Optimal annual body mass index change for preventing spontaneous preterm birth in a subsequent pregnancy |
| title_short | Optimal annual body mass index change for preventing spontaneous preterm birth in a subsequent pregnancy |
| title_sort | optimal annual body mass index change for preventing spontaneous preterm birth in a subsequent pregnancy |
| url | https://doi.org/10.1038/s41598-022-22495-4 |
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