Longitudinal alterations in brain perfusion and vascular reactivity in the zQ175DN mouse model of Huntington’s disease
Abstract Background Huntington’s disease (HD) is marked by a CAG-repeat expansion in the huntingtin gene that causes neuronal dysfunction and loss, affecting mainly the striatum and the cortex. Alterations in the neurovascular coupling system have been shown to lead to dysregulated energy supply to...
Հիմնական հեղինակներ: | , , , , , , , , , , , , , , , |
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Ձևաչափ: | Հոդված |
Լեզու: | English |
Հրապարակվել է: |
BMC
2024-04-01
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Շարք: | Journal of Biomedical Science |
Խորագրեր: | |
Առցանց հասանելիություն: | https://doi.org/10.1186/s12929-024-01028-3 |