The influence of Ag+, Zn2+ and Cu2+ exchanged zeolite on antimicrobial and long term in vitro stability of medical grade polyether polyurethane
This study aims to investigate the limitations and applicability of different ion exchanged zeolites as antimicrobial additive in thermoplastic polyether type polyurethanes. These composites were designed to improve the health quality of hospitalized patients by expressing both biocompatibility and...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Budapest University of Technology
2011-12-01
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| Series: | eXPRESS Polymer Letters |
| Subjects: | |
| Online Access: | http://www.expresspolymlett.com/letolt.php?file=EPL-0002547&mi=cd |
| _version_ | 1811319248104980480 |
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| author | R. E. Aune Gy. Czel M. M. Perez-Madrigal P. Kaali S. Karlsson E. Stromberg |
| author_facet | R. E. Aune Gy. Czel M. M. Perez-Madrigal P. Kaali S. Karlsson E. Stromberg |
| author_sort | R. E. Aune |
| collection | DOAJ |
| description | This study aims to investigate the limitations and applicability of different ion exchanged zeolites as antimicrobial additive in thermoplastic polyether type polyurethanes. These composites were designed to improve the health quality of hospitalized patients by expressing both biocompatibility and relevant antimicrobial activity. The zeolites were exchanged with silver, copper and zinc ions and single, binary and ternary ion-exchanged zeolite-polyurethane composites were prepared. The antimicrobial activity and the resistance of the composites against the human environment play vital role in the applicability of the materials as a medical device therefore these properties were investigated. The antimicrobial test were performed on Methicillin-resistant Staphylococcus aureus, Pseudomonas aeruginosa and Candida tropicalis. The tests showed that the efficiency of the silver ions is superior to the other single ionic systems. Besides, the binary and ternary ion-exchanged samples had similar antimicrobial efficiency regardless the type of the ions in the zeolite. The biocompatibility tests were carried out in-vitro in artificial body fluids for a period of 12 weeks. As a result of the invitro test, degradation of the composites were observed and the structural changes of the materials were detected and described by Scanning Electron Microscopy, Contact Angle measurements and Attenuated Total Reflection Fourier Transform Infrared Spectroscopy. |
| first_indexed | 2024-04-13T12:39:27Z |
| format | Article |
| id | doaj.art-dd62f224d3ce4cf8b09d00f49397444b |
| institution | Directory Open Access Journal |
| issn | 1788-618X |
| language | English |
| last_indexed | 2024-04-13T12:39:27Z |
| publishDate | 2011-12-01 |
| publisher | Budapest University of Technology |
| record_format | Article |
| series | eXPRESS Polymer Letters |
| spelling | doaj.art-dd62f224d3ce4cf8b09d00f49397444b2022-12-22T02:46:33ZengBudapest University of TechnologyeXPRESS Polymer Letters1788-618X2011-12-015121028104010.3144/expresspolymlett.2011.101The influence of Ag+, Zn2+ and Cu2+ exchanged zeolite on antimicrobial and long term in vitro stability of medical grade polyether polyurethaneR. E. AuneGy. CzelM. M. Perez-MadrigalP. KaaliS. KarlssonE. StrombergThis study aims to investigate the limitations and applicability of different ion exchanged zeolites as antimicrobial additive in thermoplastic polyether type polyurethanes. These composites were designed to improve the health quality of hospitalized patients by expressing both biocompatibility and relevant antimicrobial activity. The zeolites were exchanged with silver, copper and zinc ions and single, binary and ternary ion-exchanged zeolite-polyurethane composites were prepared. The antimicrobial activity and the resistance of the composites against the human environment play vital role in the applicability of the materials as a medical device therefore these properties were investigated. The antimicrobial test were performed on Methicillin-resistant Staphylococcus aureus, Pseudomonas aeruginosa and Candida tropicalis. The tests showed that the efficiency of the silver ions is superior to the other single ionic systems. Besides, the binary and ternary ion-exchanged samples had similar antimicrobial efficiency regardless the type of the ions in the zeolite. The biocompatibility tests were carried out in-vitro in artificial body fluids for a period of 12 weeks. As a result of the invitro test, degradation of the composites were observed and the structural changes of the materials were detected and described by Scanning Electron Microscopy, Contact Angle measurements and Attenuated Total Reflection Fourier Transform Infrared Spectroscopy.http://www.expresspolymlett.com/letolt.php?file=EPL-0002547&mi=cdBiopolymersbiocompositesBody fluidIon-exchanged zeoliteAntibacterialIn-vitro test |
| spellingShingle | R. E. Aune Gy. Czel M. M. Perez-Madrigal P. Kaali S. Karlsson E. Stromberg The influence of Ag+, Zn2+ and Cu2+ exchanged zeolite on antimicrobial and long term in vitro stability of medical grade polyether polyurethane eXPRESS Polymer Letters Biopolymers biocomposites Body fluid Ion-exchanged zeolite Antibacterial In-vitro test |
| title | The influence of Ag+, Zn2+ and Cu2+ exchanged zeolite on antimicrobial and long term in vitro stability of medical grade polyether polyurethane |
| title_full | The influence of Ag+, Zn2+ and Cu2+ exchanged zeolite on antimicrobial and long term in vitro stability of medical grade polyether polyurethane |
| title_fullStr | The influence of Ag+, Zn2+ and Cu2+ exchanged zeolite on antimicrobial and long term in vitro stability of medical grade polyether polyurethane |
| title_full_unstemmed | The influence of Ag+, Zn2+ and Cu2+ exchanged zeolite on antimicrobial and long term in vitro stability of medical grade polyether polyurethane |
| title_short | The influence of Ag+, Zn2+ and Cu2+ exchanged zeolite on antimicrobial and long term in vitro stability of medical grade polyether polyurethane |
| title_sort | influence of ag zn2 and cu2 exchanged zeolite on antimicrobial and long term in vitro stability of medical grade polyether polyurethane |
| topic | Biopolymers biocomposites Body fluid Ion-exchanged zeolite Antibacterial In-vitro test |
| url | http://www.expresspolymlett.com/letolt.php?file=EPL-0002547&mi=cd |
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