Intrinsic disorder in PRAME and its role in uveal melanoma

Intrinsic disorder in PRAME and its role in uveal melanoma

Abstract Introduction The PReferentially expressed Antigen in MElanoma (PRAME) protein has been shown to be an independent biomarker for increased risk of metastasis in Class 1 uveal melanomas (UM). Intrinsically disordered proteins and regions of proteins (IDPs/IDPRs) are proteins that do not have...

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Bibliographic Details
Main Authors:	Michael Antonietti, David J. Taylor Gonzalez, Mak Djulbegovic, Guy W. Dayhoff, Vladimir N. Uversky, Carol L. Shields, Carol L. Karp
Format:	Article
Language:	English
Published:	BMC 2023-08-01
Series:	Cell Communication and Signaling
Subjects:	Uveal melanoma Intrinsically disordered protein Disorder-to-order-transition PRAME PReferentially expressed Antigen in Melanoma
Online Access:	https://doi.org/10.1186/s12964-023-01197-y

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