Proper modulation of AHR signaling is necessary for establishing neural connectivity and oligodendrocyte precursor cell development in the embryonic zebrafish brain

Proper modulation of AHR signaling is necessary for establishing neural connectivity and oligodendrocyte precursor cell development in the embryonic zebrafish brain

2,3,7,8-tetrachlorodibenzo-[p]-dioxin (TCDD) is a persistent global pollutant that exhibits a high affinity for the aryl hydrocarbon receptor (AHR), a ligand activated transcription factor. Epidemiological studies have associated AHR agonist exposure with multiple human neuropathologies. Consistent...

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Bibliographic Details
Main Authors: Nathan R. Martin, Ratna Patel, Michelle E. Kossack, Lucy Tian, Manuel A. Camarillo, Layra G. Cintrón-Rivera, Joseph C. Gawdzik, Monica S. Yue, Favour O. Nwagugo, Loes M. H. Elemans, Jessica S. Plavicki
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Molecular Neuroscience
Subjects:
TCDD
dioxin
aryl hydrocarbon receptor
ahr2
neurotoxicity
olig2
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2022.1032302/full

Internet

https://www.frontiersin.org/articles/10.3389/fnmol.2022.1032302/full

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