Toxicity of diclofenac sodium salt in Yucatan minipigs (Sus scrofa) following 4 weeks of daily intramuscular administration

Toxicity of diclofenac sodium salt in Yucatan minipigs (Sus scrofa) following 4 weeks of daily intramuscular administration

Diclofenac sodium salt (DSS) is a widely used nonsteroidal anti-inflammatory drug. The present study was performed under good laboratory practice (GLP) regulations to investigate the toxicity of DSS after 4 weeks of repeated intramuscular administration at doses of 0, 2, 10, or 20 mg/kg/day in 32 mi...

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Bibliographic Details
Main Authors: Hyung-Sun Kim, Goo-Hwa Kang, Mi-Jin Yang, Hee-Jeong Ahn, Su-Cheol Han, Jeong Ho Hwang
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Toxicology Reports
Subjects:
Diclofenac sodium salt
Minipig
No-observed-adverse-effect level
4-Week repeated toxicity
Online Access:http://www.sciencedirect.com/science/article/pii/S2214750021000391

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