Descemet′s membrane endothelial keratoplasty in south Asian population
Purpose: To evaluate visual outcomes, endothelial cell density and complications following Descemet′s membrane endothelial keratoplasty (DMEK). Methods: This study included 40 consecutive eyes that underwent DMEK for various pathologies involving the corneal endothelium. Best corrected visual acuit...
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Language: | English |
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Knowledge E
2016-01-01
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Series: | Journal of Ophthalmic & Vision Research |
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Online Access: | http://www.jovr.org/article.asp?issn=2008-322X;year=2016;volume=11;issue=4;spage=368;epage=371;aulast=Bhandari |
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author | Vipul Bhandari Jagdeesh K Reddy Prateek Chougale |
author_facet | Vipul Bhandari Jagdeesh K Reddy Prateek Chougale |
author_sort | Vipul Bhandari |
collection | DOAJ |
description | Purpose: To evaluate visual outcomes, endothelial cell density and complications following Descemet′s membrane endothelial keratoplasty (DMEK).
Methods: This study included 40 consecutive eyes that underwent DMEK for various pathologies involving the corneal endothelium. Best corrected visual acuity (BCVA) and endothelial cell density (ECD) were measured and compared before and 6 months after surgery.
Results: Out of 40 eyes, 34 eyes (85%) had BCVA ranging from 0.5 to 0.7 LogMAR 6 months postoperatively. Mean donor ECD was 2367.96 ± 47.87 (range, 2314.0-2472.0) cells/mm 2 preoperatively, which was reduced to 1798.42 ± 45.79 (range, 1736.0-1902.0) cells/mm 2 6 months after DMEK surgery, indicating a mean reduction of 569.54 cells/mm 2 (24%) in ECD.
Conclusion: DMEK is an emerging and a more advanced alternative to penetrating keratoplasty (PKP) and Descemet′s stripping endothelial keratoplasty (DSEK) for corneal pathologies involving the corneal endothelium. Compared to PK and DSEK, however, DMEK has a longer learning curve, and its safety and efficacy need to be confirmed through more experience on a large volume of cases. |
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institution | Directory Open Access Journal |
issn | 2008-322X |
language | English |
last_indexed | 2024-04-11T08:44:44Z |
publishDate | 2016-01-01 |
publisher | Knowledge E |
record_format | Article |
series | Journal of Ophthalmic & Vision Research |
spelling | doaj.art-dd6bbc373efa4870a962c47dfd11394e2022-12-22T04:34:00ZengKnowledge EJournal of Ophthalmic & Vision Research2008-322X2016-01-0111436837110.4103/2008-322X.194072Descemet′s membrane endothelial keratoplasty in south Asian populationVipul BhandariJagdeesh K ReddyPrateek ChougalePurpose: To evaluate visual outcomes, endothelial cell density and complications following Descemet′s membrane endothelial keratoplasty (DMEK). Methods: This study included 40 consecutive eyes that underwent DMEK for various pathologies involving the corneal endothelium. Best corrected visual acuity (BCVA) and endothelial cell density (ECD) were measured and compared before and 6 months after surgery. Results: Out of 40 eyes, 34 eyes (85%) had BCVA ranging from 0.5 to 0.7 LogMAR 6 months postoperatively. Mean donor ECD was 2367.96 ± 47.87 (range, 2314.0-2472.0) cells/mm 2 preoperatively, which was reduced to 1798.42 ± 45.79 (range, 1736.0-1902.0) cells/mm 2 6 months after DMEK surgery, indicating a mean reduction of 569.54 cells/mm 2 (24%) in ECD. Conclusion: DMEK is an emerging and a more advanced alternative to penetrating keratoplasty (PKP) and Descemet′s stripping endothelial keratoplasty (DSEK) for corneal pathologies involving the corneal endothelium. Compared to PK and DSEK, however, DMEK has a longer learning curve, and its safety and efficacy need to be confirmed through more experience on a large volume of cases.http://www.jovr.org/article.asp?issn=2008-322X;year=2016;volume=11;issue=4;spage=368;epage=371;aulast=BhandariDescemet′s Membrane; Corneal Endothelium; Descemet′s Membrane Endothelial Keratoplasty |
spellingShingle | Vipul Bhandari Jagdeesh K Reddy Prateek Chougale Descemet′s membrane endothelial keratoplasty in south Asian population Journal of Ophthalmic & Vision Research Descemet′s Membrane; Corneal Endothelium; Descemet′s Membrane Endothelial Keratoplasty |
title | Descemet′s membrane endothelial keratoplasty in south Asian population |
title_full | Descemet′s membrane endothelial keratoplasty in south Asian population |
title_fullStr | Descemet′s membrane endothelial keratoplasty in south Asian population |
title_full_unstemmed | Descemet′s membrane endothelial keratoplasty in south Asian population |
title_short | Descemet′s membrane endothelial keratoplasty in south Asian population |
title_sort | descemet s membrane endothelial keratoplasty in south asian population |
topic | Descemet′s Membrane; Corneal Endothelium; Descemet′s Membrane Endothelial Keratoplasty |
url | http://www.jovr.org/article.asp?issn=2008-322X;year=2016;volume=11;issue=4;spage=368;epage=371;aulast=Bhandari |
work_keys_str_mv | AT vipulbhandari descemetsmembraneendothelialkeratoplastyinsouthasianpopulation AT jagdeeshkreddy descemetsmembraneendothelialkeratoplastyinsouthasianpopulation AT prateekchougale descemetsmembraneendothelialkeratoplastyinsouthasianpopulation |