Descemet′s membrane endothelial keratoplasty in south Asian population

Purpose: To evaluate visual outcomes, endothelial cell density and complications following Descemet′s membrane endothelial keratoplasty (DMEK). Methods: This study included 40 consecutive eyes that underwent DMEK for various pathologies involving the corneal endothelium. Best corrected visual acuit...

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Main Authors: Vipul Bhandari, Jagdeesh K Reddy, Prateek Chougale
Format: Article
Language:English
Published: Knowledge E 2016-01-01
Series:Journal of Ophthalmic & Vision Research
Subjects:
Online Access:http://www.jovr.org/article.asp?issn=2008-322X;year=2016;volume=11;issue=4;spage=368;epage=371;aulast=Bhandari
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author Vipul Bhandari
Jagdeesh K Reddy
Prateek Chougale
author_facet Vipul Bhandari
Jagdeesh K Reddy
Prateek Chougale
author_sort Vipul Bhandari
collection DOAJ
description Purpose: To evaluate visual outcomes, endothelial cell density and complications following Descemet′s membrane endothelial keratoplasty (DMEK). Methods: This study included 40 consecutive eyes that underwent DMEK for various pathologies involving the corneal endothelium. Best corrected visual acuity (BCVA) and endothelial cell density (ECD) were measured and compared before and 6 months after surgery. Results: Out of 40 eyes, 34 eyes (85%) had BCVA ranging from 0.5 to 0.7 LogMAR 6 months postoperatively. Mean donor ECD was 2367.96 ± 47.87 (range, 2314.0-2472.0) cells/mm 2 preoperatively, which was reduced to 1798.42 ± 45.79 (range, 1736.0-1902.0) cells/mm 2 6 months after DMEK surgery, indicating a mean reduction of 569.54 cells/mm 2 (24%) in ECD. Conclusion: DMEK is an emerging and a more advanced alternative to penetrating keratoplasty (PKP) and Descemet′s stripping endothelial keratoplasty (DSEK) for corneal pathologies involving the corneal endothelium. Compared to PK and DSEK, however, DMEK has a longer learning curve, and its safety and efficacy need to be confirmed through more experience on a large volume of cases.
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spelling doaj.art-dd6bbc373efa4870a962c47dfd11394e2022-12-22T04:34:00ZengKnowledge EJournal of Ophthalmic & Vision Research2008-322X2016-01-0111436837110.4103/2008-322X.194072Descemet′s membrane endothelial keratoplasty in south Asian populationVipul BhandariJagdeesh K ReddyPrateek ChougalePurpose: To evaluate visual outcomes, endothelial cell density and complications following Descemet′s membrane endothelial keratoplasty (DMEK). Methods: This study included 40 consecutive eyes that underwent DMEK for various pathologies involving the corneal endothelium. Best corrected visual acuity (BCVA) and endothelial cell density (ECD) were measured and compared before and 6 months after surgery. Results: Out of 40 eyes, 34 eyes (85%) had BCVA ranging from 0.5 to 0.7 LogMAR 6 months postoperatively. Mean donor ECD was 2367.96 ± 47.87 (range, 2314.0-2472.0) cells/mm 2 preoperatively, which was reduced to 1798.42 ± 45.79 (range, 1736.0-1902.0) cells/mm 2 6 months after DMEK surgery, indicating a mean reduction of 569.54 cells/mm 2 (24%) in ECD. Conclusion: DMEK is an emerging and a more advanced alternative to penetrating keratoplasty (PKP) and Descemet′s stripping endothelial keratoplasty (DSEK) for corneal pathologies involving the corneal endothelium. Compared to PK and DSEK, however, DMEK has a longer learning curve, and its safety and efficacy need to be confirmed through more experience on a large volume of cases.http://www.jovr.org/article.asp?issn=2008-322X;year=2016;volume=11;issue=4;spage=368;epage=371;aulast=BhandariDescemet′s Membrane; Corneal Endothelium; Descemet′s Membrane Endothelial Keratoplasty
spellingShingle Vipul Bhandari
Jagdeesh K Reddy
Prateek Chougale
Descemet′s membrane endothelial keratoplasty in south Asian population
Journal of Ophthalmic & Vision Research
Descemet′s Membrane; Corneal Endothelium; Descemet′s Membrane Endothelial Keratoplasty
title Descemet′s membrane endothelial keratoplasty in south Asian population
title_full Descemet′s membrane endothelial keratoplasty in south Asian population
title_fullStr Descemet′s membrane endothelial keratoplasty in south Asian population
title_full_unstemmed Descemet′s membrane endothelial keratoplasty in south Asian population
title_short Descemet′s membrane endothelial keratoplasty in south Asian population
title_sort descemet s membrane endothelial keratoplasty in south asian population
topic Descemet′s Membrane; Corneal Endothelium; Descemet′s Membrane Endothelial Keratoplasty
url http://www.jovr.org/article.asp?issn=2008-322X;year=2016;volume=11;issue=4;spage=368;epage=371;aulast=Bhandari
work_keys_str_mv AT vipulbhandari descemetsmembraneendothelialkeratoplastyinsouthasianpopulation
AT jagdeeshkreddy descemetsmembraneendothelialkeratoplastyinsouthasianpopulation
AT prateekchougale descemetsmembraneendothelialkeratoplastyinsouthasianpopulation