Role of metalloproteases in the CD95 signaling pathways

Role of metalloproteases in the CD95 signaling pathways

CD95L (also known as FasL or CD178) is a member of the tumor necrosis family (TNF) superfamily. Although this transmembrane ligand has been mainly considered as a potent apoptotic inducer in CD95 (Fas)-expressing cells, more recent studies pointed out its role in the implementation of non-apoptotic...

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Bibliographic Details
Main Authors: Laurent Devel, Nicolas Guedeney, Sarah Bregant, Animesh Chowdhury, Mickael Jean, Patrick Legembre
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Immunology
Subjects:
ADAM
CD95L
cancer
cleavage
inflammation
MMP
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1074099/full

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