The EGFR-HSF1 axis accelerates the tumorigenesis of pancreatic cancer

The EGFR-HSF1 axis accelerates the tumorigenesis of pancreatic cancer

Abstract Background Pancreatic ductal adenocarcinoma (PDAC) is one of the most malignant diseases because of its non-symptomatic tumorigenesis. We previous found heat shock factor 1 (HSF1) was critical for PDAC progression and the aim of this study was to clarified the mechanisms on early activation...

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Bibliographic Details
Main Authors:	Weikun Qian, Ke Chen, Tao Qin, Ying Xiao, Jie Li, Yangyang Yue, Cancan Zhou, Jiguang Ma, Wanxing Duan, Jianjun Lei, Liang Han, Li Li, Xin Shen, Zheng Wu, Qingyong Ma, Zheng Wang
Format:	Article
Language:	English
Published:	BMC 2021-01-01
Series:	Journal of Experimental & Clinical Cancer Research
Subjects:	Pancreatic ductal adenocarcinoma Heat shock factor 1 Epidermal growth factor receptor Transgenic mice Tumorigenesis
Online Access:	https://doi.org/10.1186/s13046-020-01823-4

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