A conflict of interest: the evolutionary arms race between mammalian APOBEC3 and lentiviral Vif

A conflict of interest: the evolutionary arms race between mammalian APOBEC3 and lentiviral Vif

Abstract Apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3 (APOBEC3) proteins are mammalian-specific cellular deaminases and have a robust ability to restrain lentivirus replication. To antagonize APOBEC3-mediated antiviral action, lentiviruses have acquired viral infectivity factor...

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Bibliographic Details
Main Authors: Yusuke Nakano, Hirofumi Aso, Andrew Soper, Eri Yamada, Miyu Moriwaki, Guillermo Juarez-Fernandez, Yoshio Koyanagi, Kei Sato
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Retrovirology
Subjects:
Vif
APOBEC3
Lentivirus
Mammal
Evolutionary arms race
Online Access:http://link.springer.com/article/10.1186/s12977-017-0355-4

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