Corticortophin releasing factor 2 receptor agonist treatment significantly slows disease progression in mdx mice

<p>Abstract</p> <p>Background</p> <p>Duchenne muscular dystrophy results from mutation of the dystrophin gene, causing skeletal and cardiac muscle loss of function. The mdx mouse model of Duchenne muscular dystrophy is widely utilized to evaluate the potential of therap...

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Main Authors: Stevens Paula J, Demuth Jeffrey P, Thacker Robert I, Gropp Kathryn E, Dietrich Jefferey A, Reichart Deborah L, Dolan Elizabeth T, Lefever Frank R, Hinkle Richard T, Qu Xiaoyan A, Varbanov Alex R, Wang Feng, Isfort Robert J
Format: Article
Language:English
Published: BMC 2007-07-01
Series:BMC Medicine
Online Access:http://www.biomedcentral.com/1741-7015/5/18