Association of Life Style and Sociodemographic Parameters with Plasma Heavy Metals in Apparently Healthy Adult in Ebonyi State, South East Nigeria
Introduction: Lifestyle and sociodemographic parameters have been recognised to play important roles in human exposure to heavy metals and metal toxicity in both environmental and occupational setting. Aim: To determine the association of life style factors and sociodemographic parameters with...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2020-07-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/13832/43784_CE[Ra1]_F(SHU)_PF1(ShG_SHU)_GC(Su_SL)_PN(SL).pdf |
| Summary: | Introduction: Lifestyle and sociodemographic parameters have
been recognised to play important roles in human exposure
to heavy metals and metal toxicity in both environmental and
occupational setting.
Aim: To determine the association of life style factors and
sociodemographic parameters with plasma heavy metals;
arsenic (As), cadmium (Cd), copper (Cu), iron (Fe), lead (Pb),
nickel (Ni), selenium (Se) and zinc (Zn) in apparently healthy
individuals.
Materials and Methods: Randomly selected subjects (n=301)
from 130 political wards in the 13 Local Government Area
of the State, were studied. Structured questionnaires were
used to collect sociodemographic data while anthropometric
parameters were collected using standard techniques. Metal
concentrations were determined in blood plasma using atomic
absorption spectrophotometer. One-way Analysis of Variance
(One-way ANOVA) was use to analyse the data and p ≤0.05 was
considered significant.
Results: The observed mean levels of heavy metals were: As
(0.21±0.02), Cd (0.37±0.04), Cu (156.49±2.16), Fe (132.66±2.14),
Pb (1.13±0.12), Ni (0.06±001), Se (0.14±0.01) and Zn (94.32±1.10)
µg/dL. Plasma levels of heavy metals were affected by body
mass index (BMI), age, educational level and occupation.
However, there was no significant (p>0.05) difference in the
levels of heavy metals between males and females, smokers
and non-smokers and alcohol consumers and non-consumers.
Plasma As and Cd were significantly negatively associated with
age and BMI.
Conclusion: It is concluded that indicators of socioeconomic
status have effect plasma levels of heavy metals with levels of
toxic metals raised while the levels of essential trace elements
were low. Dietary diversification in addition to prevention of
exposure is advocated. |
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| ISSN: | 2249-782X 0973-709X |