Rapid loss of early antigen-presenting activity of lymph node dendritic cells against Ag85A protein following Mycobacterium bovis BCG infection

Rapid loss of early antigen-presenting activity of lymph node dendritic cells against Ag85A protein following Mycobacterium bovis BCG infection

Abstract Background Control of Mycobacterium tuberculosis (Mtb) infection requires CD4+ T-cell responses and major histocompatibility complex class II (MHC II) presentation of Mtb antigens (Ags). Dendritic cells (DCs) are the most potent of the Ag-presenting cells and are central to the initiation o...

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Bibliographic Details
Main Authors: Zhengzhong Xu, Aihong Xia, Xin Li, Zhaocheng Zhu, Yechi Shen, Shanshan Jin, Tian Lan, Yuqing Xie, Han Wu, Chuang Meng, Lin Sun, Yuelan Yin, Xiang Chen, Xinan Jiao
Format: Article
Language:English
Published: BMC 2018-06-01
Series:BMC Immunology
Subjects:
Ag-presenting activity
Dendritic cell
M. bovis BCG
Major histocompatibility complex class II
In vivo
Online Access:http://link.springer.com/article/10.1186/s12865-018-0258-8

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