Conjunctival and bulbar sporotrichosis as Parinaud’s oculoglandular syndrome acquired by blood inoculation
Parinaud’s oculoglandular syndrome (POS) is a clinical condition characterized by granulomatous conjunctivitis associated with homolateral neck pain and anterior preauricular lymphadenopathy. Several reports of this condition occurred and some bacterial etiological agents were identified. However, f...
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| Format: | Article |
| Language: | English |
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German Medical Science GMS Publishing House
2021-01-01
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| Series: | GMS Ophthalmology Cases |
| Online Access: | http://www.egms.de/static/en/journals/oc/2021-11/oc000175.shtml |
| _version_ | 1818450315506089984 |
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| author | Liborio Neto, Adail Orrith Rubim Caetano, Tiago Pestana Gervasio, Nairacyr Hans Camargo Carneiro, Rachel |
| author_facet | Liborio Neto, Adail Orrith Rubim Caetano, Tiago Pestana Gervasio, Nairacyr Hans Camargo Carneiro, Rachel |
| author_sort | Liborio Neto, Adail Orrith |
| collection | DOAJ |
| description | Parinaud’s oculoglandular syndrome (POS) is a clinical condition characterized by granulomatous conjunctivitis associated with homolateral neck pain and anterior preauricular lymphadenopathy. Several reports of this condition occurred and some bacterial etiological agents were identified. However, fungal infections have also been associated, especially sporotrichosis. A 40-year-old female patient complained about a “little ball” in the lower eyelid of the left eye. On ocular examination, visual acuity and fundoscopy were normal. The biomicroscopy revealed a granulomatous lesion in the lower eyelid of the left eye associated with yellowish discharge. The patient returned the next day, reporting worsening of the condition accompanied by low fever, malaise, prear and submandibular lymphadenomegaly. The examination showed the evolution of conjunctival edema and various conjunctival granulomas in the lower and upper tarsus of the left eye, a clinical picture compatible with POS. In the investigation of the clinical history, the patient remembered an episode of contact with blood of cats. During the investigation, we discarded differential diagnoses such as tuberculosis, toxoplasmosis, CMV, herpes virus and . Serology was positive for . Treatment with itraconazole 100 mg once daily was started. By the eighth week, the conjunctival granulomas had disappeared, and the medication was discontinued after 90 days of treatment, after about 2 weeks of total remission. According to the literature, there are no cases of primarily ocular manifestation of blood sporotrichosis transmission. However, in the report, the form of transmission of the disease occurred by inoculation by direct contact with the blood of contaminated cats. |
| first_indexed | 2024-12-14T20:49:21Z |
| format | Article |
| id | doaj.art-dd7fd94ee2d04fc9a63604de318d8b46 |
| institution | Directory Open Access Journal |
| issn | 2193-1496 |
| language | English |
| last_indexed | 2024-12-14T20:49:21Z |
| publishDate | 2021-01-01 |
| publisher | German Medical Science GMS Publishing House |
| record_format | Article |
| series | GMS Ophthalmology Cases |
| spelling | doaj.art-dd7fd94ee2d04fc9a63604de318d8b462022-12-21T22:47:52ZengGerman Medical Science GMS Publishing HouseGMS Ophthalmology Cases2193-14962021-01-0111Doc0210.3205/oc000175Conjunctival and bulbar sporotrichosis as Parinaud’s oculoglandular syndrome acquired by blood inoculationLiborio Neto, Adail Orrith0Rubim Caetano, Tiago1Pestana Gervasio, Nairacyr Hans2Camargo Carneiro, Rachel3Federal University of Rio de Janeiro, Campus Macaé (UFRJ), Rio de Janeiro, BrazilFederal University of Rio de Janeiro, Campus Macaé (UFRJ), Rio de Janeiro, BrazilFederal University of Rio de Janeiro, Campus Macaé (UFRJ), Rio de Janeiro, BrazilFederal University of Rio de Janeiro, Campus Macaé (UFRJ), Rio de Janeiro, BrazilParinaud’s oculoglandular syndrome (POS) is a clinical condition characterized by granulomatous conjunctivitis associated with homolateral neck pain and anterior preauricular lymphadenopathy. Several reports of this condition occurred and some bacterial etiological agents were identified. However, fungal infections have also been associated, especially sporotrichosis. A 40-year-old female patient complained about a “little ball” in the lower eyelid of the left eye. On ocular examination, visual acuity and fundoscopy were normal. The biomicroscopy revealed a granulomatous lesion in the lower eyelid of the left eye associated with yellowish discharge. The patient returned the next day, reporting worsening of the condition accompanied by low fever, malaise, prear and submandibular lymphadenomegaly. The examination showed the evolution of conjunctival edema and various conjunctival granulomas in the lower and upper tarsus of the left eye, a clinical picture compatible with POS. In the investigation of the clinical history, the patient remembered an episode of contact with blood of cats. During the investigation, we discarded differential diagnoses such as tuberculosis, toxoplasmosis, CMV, herpes virus and . Serology was positive for . Treatment with itraconazole 100 mg once daily was started. By the eighth week, the conjunctival granulomas had disappeared, and the medication was discontinued after 90 days of treatment, after about 2 weeks of total remission. According to the literature, there are no cases of primarily ocular manifestation of blood sporotrichosis transmission. However, in the report, the form of transmission of the disease occurred by inoculation by direct contact with the blood of contaminated cats.http://www.egms.de/static/en/journals/oc/2021-11/oc000175.shtml |
| spellingShingle | Liborio Neto, Adail Orrith Rubim Caetano, Tiago Pestana Gervasio, Nairacyr Hans Camargo Carneiro, Rachel Conjunctival and bulbar sporotrichosis as Parinaud’s oculoglandular syndrome acquired by blood inoculation GMS Ophthalmology Cases |
| title | Conjunctival and bulbar sporotrichosis as Parinaud’s oculoglandular syndrome acquired by blood inoculation |
| title_full | Conjunctival and bulbar sporotrichosis as Parinaud’s oculoglandular syndrome acquired by blood inoculation |
| title_fullStr | Conjunctival and bulbar sporotrichosis as Parinaud’s oculoglandular syndrome acquired by blood inoculation |
| title_full_unstemmed | Conjunctival and bulbar sporotrichosis as Parinaud’s oculoglandular syndrome acquired by blood inoculation |
| title_short | Conjunctival and bulbar sporotrichosis as Parinaud’s oculoglandular syndrome acquired by blood inoculation |
| title_sort | conjunctival and bulbar sporotrichosis as parinaud s oculoglandular syndrome acquired by blood inoculation |
| url | http://www.egms.de/static/en/journals/oc/2021-11/oc000175.shtml |
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