The protective effects of pericyte-derived microvesicles on vascular endothelial functions via CTGF delivery in sepsis

The protective effects of pericyte-derived microvesicles on vascular endothelial functions via CTGF delivery in sepsis

Abstract Background It is well known that sepsis is a prevalent severe disease caused by infection and the treatment strategies are limited. Recently pericyte-derived microvesicles (PMVs) were confirmed to be therapeutic in many diseases, whether PMVs can protect vascular endothelial cell (VEC) inju...

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Bibliographic Details
Main Authors: Henan Zhou, Danyang Zheng, Hongchen Wang, Yue Wu, Xiaoyong Peng, Qinghui Li, Tao Li, Liangming Liu
Format: Article
Language:English
Published: BMC 2021-11-01
Series:Cell Communication and Signaling
Subjects:
Pericyte
Microvesicles
Sepsis
CTGF
Online Access:https://doi.org/10.1186/s12964-021-00795-y

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