Loss of Acid sensing ion channel-1a and bicarbonate administration attenuate the severity of traumatic brain injury.

Loss of Acid sensing ion channel-1a and bicarbonate administration attenuate the severity of traumatic brain injury.

Traumatic brain injury (TBI) is a common cause of morbidity and mortality in people of all ages. Following the acute mechanical insult, TBI evolves over the ensuing minutes and days. Understanding the secondary factors that contribute to TBI might suggest therapeutic strategies to reduce the long-te...

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Bibliographic Details
Main Authors: Terry Yin, Timothy E Lindley, Gregory W Albert, Raheel Ahmed, Peter B Schmeiser, M Sean Grady, Matthew A Howard, Michael J Welsh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3753246?pdf=render

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