Systemic treatment for hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is one of the most common cancers with high mortality worldwide. Treatment options for patients with advanced stage HCC remain a great challenge. However, novel agents especially small molecule tyrosine kinase inhibitor and innovative immunotherapy demonstrate new prom...

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Main Authors: Manushi Aggarwal, Abeer Arain, Zhaohui Jin
Format: Article
Language:English
Published: Wiley 2018-09-01
Series:Chronic Diseases and Translational Medicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2095882X18300471
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author Manushi Aggarwal
Abeer Arain
Zhaohui Jin
author_facet Manushi Aggarwal
Abeer Arain
Zhaohui Jin
author_sort Manushi Aggarwal
collection DOAJ
description Hepatocellular carcinoma (HCC) is one of the most common cancers with high mortality worldwide. Treatment options for patients with advanced stage HCC remain a great challenge. However, novel agents especially small molecule tyrosine kinase inhibitor and innovative immunotherapy demonstrate new promising therapeutic options for these patients. This review article summarizes systemic treatment options evaluated in HCC focusing on the most recently published data and ongoing studies. Keywords: Hepatocellular carcinoma, Systemic treatment, Immunotherapy, Tyrosine kinase inhibitor
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spelling doaj.art-dd85b95f2f214bc6854270b02bc26dff2022-12-22T03:37:49ZengWileyChronic Diseases and Translational Medicine2095-882X2018-09-0143148155Systemic treatment for hepatocellular carcinomaManushi Aggarwal0Abeer Arain1Zhaohui Jin2Carle Cancer Center, Carle Foundation Hospital, 509 W. University Avenue, Urbana, IL 61801, USA; Department of Internal Medicine, University of Illinois College of Medicine at Urbana-Champaign, Urbana, IL 61801, USACarle Cancer Center, Carle Foundation Hospital, 509 W. University Avenue, Urbana, IL 61801, USA; Department of Internal Medicine, University of Illinois College of Medicine at Urbana-Champaign, Urbana, IL 61801, USACarle Cancer Center, Carle Foundation Hospital, 509 W. University Avenue, Urbana, IL 61801, USA; Department of Internal Medicine, University of Illinois College of Medicine at Urbana-Champaign, Urbana, IL 61801, USA; Corresponding author. Carle Cancer Center, Carle Foundation Hospital, 509 W. University Avenue, Urbana, IL, 61801, USA.Hepatocellular carcinoma (HCC) is one of the most common cancers with high mortality worldwide. Treatment options for patients with advanced stage HCC remain a great challenge. However, novel agents especially small molecule tyrosine kinase inhibitor and innovative immunotherapy demonstrate new promising therapeutic options for these patients. This review article summarizes systemic treatment options evaluated in HCC focusing on the most recently published data and ongoing studies. Keywords: Hepatocellular carcinoma, Systemic treatment, Immunotherapy, Tyrosine kinase inhibitorhttp://www.sciencedirect.com/science/article/pii/S2095882X18300471
spellingShingle Manushi Aggarwal
Abeer Arain
Zhaohui Jin
Systemic treatment for hepatocellular carcinoma
Chronic Diseases and Translational Medicine
title Systemic treatment for hepatocellular carcinoma
title_full Systemic treatment for hepatocellular carcinoma
title_fullStr Systemic treatment for hepatocellular carcinoma
title_full_unstemmed Systemic treatment for hepatocellular carcinoma
title_short Systemic treatment for hepatocellular carcinoma
title_sort systemic treatment for hepatocellular carcinoma
url http://www.sciencedirect.com/science/article/pii/S2095882X18300471
work_keys_str_mv AT manushiaggarwal systemictreatmentforhepatocellularcarcinoma
AT abeerarain systemictreatmentforhepatocellularcarcinoma
AT zhaohuijin systemictreatmentforhepatocellularcarcinoma