Systemic treatment for hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is one of the most common cancers with high mortality worldwide. Treatment options for patients with advanced stage HCC remain a great challenge. However, novel agents especially small molecule tyrosine kinase inhibitor and innovative immunotherapy demonstrate new prom...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2018-09-01
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Series: | Chronic Diseases and Translational Medicine |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2095882X18300471 |
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author | Manushi Aggarwal Abeer Arain Zhaohui Jin |
author_facet | Manushi Aggarwal Abeer Arain Zhaohui Jin |
author_sort | Manushi Aggarwal |
collection | DOAJ |
description | Hepatocellular carcinoma (HCC) is one of the most common cancers with high mortality worldwide. Treatment options for patients with advanced stage HCC remain a great challenge. However, novel agents especially small molecule tyrosine kinase inhibitor and innovative immunotherapy demonstrate new promising therapeutic options for these patients. This review article summarizes systemic treatment options evaluated in HCC focusing on the most recently published data and ongoing studies. Keywords: Hepatocellular carcinoma, Systemic treatment, Immunotherapy, Tyrosine kinase inhibitor |
first_indexed | 2024-04-12T09:51:28Z |
format | Article |
id | doaj.art-dd85b95f2f214bc6854270b02bc26dff |
institution | Directory Open Access Journal |
issn | 2095-882X |
language | English |
last_indexed | 2024-04-12T09:51:28Z |
publishDate | 2018-09-01 |
publisher | Wiley |
record_format | Article |
series | Chronic Diseases and Translational Medicine |
spelling | doaj.art-dd85b95f2f214bc6854270b02bc26dff2022-12-22T03:37:49ZengWileyChronic Diseases and Translational Medicine2095-882X2018-09-0143148155Systemic treatment for hepatocellular carcinomaManushi Aggarwal0Abeer Arain1Zhaohui Jin2Carle Cancer Center, Carle Foundation Hospital, 509 W. University Avenue, Urbana, IL 61801, USA; Department of Internal Medicine, University of Illinois College of Medicine at Urbana-Champaign, Urbana, IL 61801, USACarle Cancer Center, Carle Foundation Hospital, 509 W. University Avenue, Urbana, IL 61801, USA; Department of Internal Medicine, University of Illinois College of Medicine at Urbana-Champaign, Urbana, IL 61801, USACarle Cancer Center, Carle Foundation Hospital, 509 W. University Avenue, Urbana, IL 61801, USA; Department of Internal Medicine, University of Illinois College of Medicine at Urbana-Champaign, Urbana, IL 61801, USA; Corresponding author. Carle Cancer Center, Carle Foundation Hospital, 509 W. University Avenue, Urbana, IL, 61801, USA.Hepatocellular carcinoma (HCC) is one of the most common cancers with high mortality worldwide. Treatment options for patients with advanced stage HCC remain a great challenge. However, novel agents especially small molecule tyrosine kinase inhibitor and innovative immunotherapy demonstrate new promising therapeutic options for these patients. This review article summarizes systemic treatment options evaluated in HCC focusing on the most recently published data and ongoing studies. Keywords: Hepatocellular carcinoma, Systemic treatment, Immunotherapy, Tyrosine kinase inhibitorhttp://www.sciencedirect.com/science/article/pii/S2095882X18300471 |
spellingShingle | Manushi Aggarwal Abeer Arain Zhaohui Jin Systemic treatment for hepatocellular carcinoma Chronic Diseases and Translational Medicine |
title | Systemic treatment for hepatocellular carcinoma |
title_full | Systemic treatment for hepatocellular carcinoma |
title_fullStr | Systemic treatment for hepatocellular carcinoma |
title_full_unstemmed | Systemic treatment for hepatocellular carcinoma |
title_short | Systemic treatment for hepatocellular carcinoma |
title_sort | systemic treatment for hepatocellular carcinoma |
url | http://www.sciencedirect.com/science/article/pii/S2095882X18300471 |
work_keys_str_mv | AT manushiaggarwal systemictreatmentforhepatocellularcarcinoma AT abeerarain systemictreatmentforhepatocellularcarcinoma AT zhaohuijin systemictreatmentforhepatocellularcarcinoma |