Angiogenic ability of human endothelial cells was decreased following senescence induction with hydrogen peroxide: possible role of vegfr-2/akt-1 signaling pathway

Angiogenic ability of human endothelial cells was decreased following senescence induction with hydrogen peroxide: possible role of vegfr-2/akt-1 signaling pathway

Abstract Background Many attempts are used to discover mechanisms driving impaired angiogenesis in age-related diseases. Angiogenesis is highly regulated by different signaling pathways. Here, we investigated the angiogenesis potential of human endothelial cells (ECs) upon exposure to hydrogen perox...

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Bibliographic Details
Main Authors: Nesa Janamo Berenjabad, Vahid Nejati, Jafar Rezaie
Format: Article
Language:English
Published: BMC 2022-07-01
Series:BMC Molecular and Cell Biology
Subjects:
Angiogenesis
HUVECs
H2O2
Age-related diseases
Senescence
Online Access:https://doi.org/10.1186/s12860-022-00435-4

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