Targeted recombination between homologous chromosomes for precise breeding in tomato
Targeted homologous recombination between parental chromosomes could facilitate precision breeding of crop plants. Here, Filler Hayutet al. show that CRISPR-Cas9 can be used to induce DNA double strand breaks in somatic tissue and achieve targeted recombination between homologs at an endogenous locu...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2017-05-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/ncomms15605 |
| _version_ | 1818750445765525504 |
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| author | Shdema Filler Hayut Cathy Melamed Bessudo Avraham A. Levy |
| author_facet | Shdema Filler Hayut Cathy Melamed Bessudo Avraham A. Levy |
| author_sort | Shdema Filler Hayut |
| collection | DOAJ |
| description | Targeted homologous recombination between parental chromosomes could facilitate precision breeding of crop plants. Here, Filler Hayutet al. show that CRISPR-Cas9 can be used to induce DNA double strand breaks in somatic tissue and achieve targeted recombination between homologs at an endogenous locus in tomato. |
| first_indexed | 2024-12-18T04:19:48Z |
| format | Article |
| id | doaj.art-dd8a49b10f844f569499b920f3ad4ff7 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-18T04:19:48Z |
| publishDate | 2017-05-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-dd8a49b10f844f569499b920f3ad4ff72022-12-21T21:21:16ZengNature PortfolioNature Communications2041-17232017-05-01811910.1038/ncomms15605Targeted recombination between homologous chromosomes for precise breeding in tomatoShdema Filler Hayut0Cathy Melamed Bessudo1Avraham A. Levy2Department of Plant and Environmental Sciences, Weizmann Institute of ScienceDepartment of Plant and Environmental Sciences, Weizmann Institute of ScienceDepartment of Plant and Environmental Sciences, Weizmann Institute of ScienceTargeted homologous recombination between parental chromosomes could facilitate precision breeding of crop plants. Here, Filler Hayutet al. show that CRISPR-Cas9 can be used to induce DNA double strand breaks in somatic tissue and achieve targeted recombination between homologs at an endogenous locus in tomato.https://doi.org/10.1038/ncomms15605 |
| spellingShingle | Shdema Filler Hayut Cathy Melamed Bessudo Avraham A. Levy Targeted recombination between homologous chromosomes for precise breeding in tomato Nature Communications |
| title | Targeted recombination between homologous chromosomes for precise breeding in tomato |
| title_full | Targeted recombination between homologous chromosomes for precise breeding in tomato |
| title_fullStr | Targeted recombination between homologous chromosomes for precise breeding in tomato |
| title_full_unstemmed | Targeted recombination between homologous chromosomes for precise breeding in tomato |
| title_short | Targeted recombination between homologous chromosomes for precise breeding in tomato |
| title_sort | targeted recombination between homologous chromosomes for precise breeding in tomato |
| url | https://doi.org/10.1038/ncomms15605 |
| work_keys_str_mv | AT shdemafillerhayut targetedrecombinationbetweenhomologouschromosomesforprecisebreedingintomato AT cathymelamedbessudo targetedrecombinationbetweenhomologouschromosomesforprecisebreedingintomato AT avrahamalevy targetedrecombinationbetweenhomologouschromosomesforprecisebreedingintomato |