The Role of Venetoclax in Relapsed/Refractory Acute Myeloid Leukemia: Past, Present, and Future Directions

Relapsed and/or refractory (R/R) acute myeloid leukemia (AML) is hallmarked by dramatic prognosis. Treatment remains challenging, with allogeneic hematopoietic stem cell transplantation (HSCT) as the only curative option. The BCL-2 inhibitor venetoclax (VEN) has proven to be a promising therapy for...

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Bibliographic Details
Main Authors: Matteo Piccini, Francesco Mannelli, Giacomo Coltro
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Bioengineering
Subjects:
Online Access:https://www.mdpi.com/2306-5354/10/5/591