Can Laparoscopic Cystectomy Improve Pregnancy Outcomes in Endometrioma? A Prospective Clinical Trial Study
Background: The purpose of this prospective study was to compare the ovarian response and pregnancy outcomesin the infertile women with endometrioma undergoing assisted reproductive technologies (ART) in twogroups, who were underwent laparoscopic cystectomy and received gonadotropin releasing hormon...
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| Format: | Article |
| Language: | English |
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Royan Institute (ACECR), Tehran
2022-07-01
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| Series: | International Journal of Fertility and Sterility |
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| Online Access: | https://www.ijfs.ir/article_247967_babf109a2d1b128d5276424736ef14f1.pdf |
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| author | Sedigheh Hosseinimousa Leili Safdarian Ashraf Aleyasin Marzieh Aghahosseini Marzieh Talebian |
| author_facet | Sedigheh Hosseinimousa Leili Safdarian Ashraf Aleyasin Marzieh Aghahosseini Marzieh Talebian |
| author_sort | Sedigheh Hosseinimousa |
| collection | DOAJ |
| description | Background: The purpose of this prospective study was to compare the ovarian response and pregnancy outcomesin the infertile women with endometrioma undergoing assisted reproductive technologies (ART) in twogroups, who were underwent laparoscopic cystectomy and received gonadotropin releasing hormone-agonist(GnRH-agonist) and who only received GnRH-agonist without any surgery.Materials and Methods: In this prospective clinical trial study, 79 infertile women with asymptomatic endometriomascyst (2-6 cm) were enrolled and randomly assigned to two groups. First group underwent laparoscopiccystectomy and received GnRH-agonist. Second group only received GnRH-agonist without any surgery. Followingovulation induction, all patients underwent intracytoplasmic sperm injection (ICSI). Different parameterssuch as the number of retrieved oocytes and embryos; were made our outcomes that analyzed using SPSS.Results: The pregnancy rate, chemical and clinical, and live birth rate were higher in the combined group,although these differences were not statistically significant (48.48% vs. 30.8%, P=0.12, 36.36% vs. 25.6%,P=0.32, 36.36% vs. 23.1%, P=0.29). The number of injections, antral follicles, retrieved oocytes, mature oocytes,total embryos, transferred embryos and duration of stimulation were similar in two groups.Conclusion: Laparoscopic cystectomy followed by receiving GnRH-agonist improves pregnancy outcomes in endometriomaprior to treatment with ART (registration number: IRCT201106116689N2). |
| first_indexed | 2024-04-14T03:23:04Z |
| format | Article |
| id | doaj.art-dd906244218640cb843bded18335e232 |
| institution | Directory Open Access Journal |
| issn | 2008-076X 2008-0778 |
| language | English |
| last_indexed | 2024-04-14T03:23:04Z |
| publishDate | 2022-07-01 |
| publisher | Royan Institute (ACECR), Tehran |
| record_format | Article |
| series | International Journal of Fertility and Sterility |
| spelling | doaj.art-dd906244218640cb843bded18335e2322022-12-22T02:15:16ZengRoyan Institute (ACECR), TehranInternational Journal of Fertility and Sterility2008-076X2008-07782022-07-0116320621010.22074/ijfs.2021.521378.1066247967Can Laparoscopic Cystectomy Improve Pregnancy Outcomes in Endometrioma? A Prospective Clinical Trial StudySedigheh Hosseinimousa0Leili Safdarian1Ashraf Aleyasin2Marzieh Aghahosseini3Marzieh Talebian4Department of Obstetrics and Gynecology and Reproductive, Shariati Hospital, Tehran University of Medical Sciences, Tehran, IranDepartment of Obstetrics and Gynecology and Reproductive, Shariati Hospital, Tehran University of Medical Sciences, Tehran, IranDepartment of Obstetrics and Gynecology and Reproductive, Shariati Hospital, Tehran University of Medical Sciences, Tehran, IranDepartment of Obstetrics and Gynecology and Reproductive, Shariati Hospital, Tehran University of Medical Sciences, Tehran, IranDepartment of Obstetrics and Gynecology, Kashan University of Medical Sciences, Kashan, IranBackground: The purpose of this prospective study was to compare the ovarian response and pregnancy outcomesin the infertile women with endometrioma undergoing assisted reproductive technologies (ART) in twogroups, who were underwent laparoscopic cystectomy and received gonadotropin releasing hormone-agonist(GnRH-agonist) and who only received GnRH-agonist without any surgery.Materials and Methods: In this prospective clinical trial study, 79 infertile women with asymptomatic endometriomascyst (2-6 cm) were enrolled and randomly assigned to two groups. First group underwent laparoscopiccystectomy and received GnRH-agonist. Second group only received GnRH-agonist without any surgery. Followingovulation induction, all patients underwent intracytoplasmic sperm injection (ICSI). Different parameterssuch as the number of retrieved oocytes and embryos; were made our outcomes that analyzed using SPSS.Results: The pregnancy rate, chemical and clinical, and live birth rate were higher in the combined group,although these differences were not statistically significant (48.48% vs. 30.8%, P=0.12, 36.36% vs. 25.6%,P=0.32, 36.36% vs. 23.1%, P=0.29). The number of injections, antral follicles, retrieved oocytes, mature oocytes,total embryos, transferred embryos and duration of stimulation were similar in two groups.Conclusion: Laparoscopic cystectomy followed by receiving GnRH-agonist improves pregnancy outcomes in endometriomaprior to treatment with ART (registration number: IRCT201106116689N2).https://www.ijfs.ir/article_247967_babf109a2d1b128d5276424736ef14f1.pdfcystectomyendometriomainfertilitygnrh-agonist |
| spellingShingle | Sedigheh Hosseinimousa Leili Safdarian Ashraf Aleyasin Marzieh Aghahosseini Marzieh Talebian Can Laparoscopic Cystectomy Improve Pregnancy Outcomes in Endometrioma? A Prospective Clinical Trial Study International Journal of Fertility and Sterility cystectomy endometrioma infertility gnrh-agonist |
| title | Can Laparoscopic Cystectomy Improve Pregnancy Outcomes in Endometrioma? A Prospective Clinical Trial Study |
| title_full | Can Laparoscopic Cystectomy Improve Pregnancy Outcomes in Endometrioma? A Prospective Clinical Trial Study |
| title_fullStr | Can Laparoscopic Cystectomy Improve Pregnancy Outcomes in Endometrioma? A Prospective Clinical Trial Study |
| title_full_unstemmed | Can Laparoscopic Cystectomy Improve Pregnancy Outcomes in Endometrioma? A Prospective Clinical Trial Study |
| title_short | Can Laparoscopic Cystectomy Improve Pregnancy Outcomes in Endometrioma? A Prospective Clinical Trial Study |
| title_sort | can laparoscopic cystectomy improve pregnancy outcomes in endometrioma a prospective clinical trial study |
| topic | cystectomy endometrioma infertility gnrh-agonist |
| url | https://www.ijfs.ir/article_247967_babf109a2d1b128d5276424736ef14f1.pdf |
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