Standardized in-vitro evaluation of CAR-T cells using acellular artificial target particles

Standardized in-vitro evaluation of CAR-T cells using acellular artificial target particles

The horizon of immunotherapy using CAR-T cells is continuously extending to treat solid tumors beyond the success in the treatment of liquid tumors. Precise in-vitro evaluations of CAR-T cells for their phenotypes, quantity and quality of activation in various tumor microenvironments including diffe...

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Bibliographic Details
Main Authors: Rona Harari-Steinfeld, V. S. S. Abhinav Ayyadevara, Lizette Cuevas, Francesco Marincola, Kyung-Ho Roh
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Immunology
Subjects:
CAR-T
in-vitro assay
potency assay
acellular
biomaterials
artificial
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.994532/full

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