miR-128-3p inhibits apoptosis and inflammation in LPS-induced sepsis by targeting TGFBR2
Sepsis is a systemic inflammatory response that can lead to the dysfunction of many organs. The aberrant expression of miRNAs is associated with the pathogenesis of sepsis. However, the biological functions of miR-128-3p in sepsis remain largely unknown, and its mechanism should be further investiga...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
De Gruyter
2021-02-01
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Series: | Open Medicine |
Subjects: | |
Online Access: | https://doi.org/10.1515/med-2021-0222 |
Summary: | Sepsis is a systemic inflammatory response that can lead to the dysfunction of many organs. The aberrant expression of miRNAs is associated with the pathogenesis of sepsis. However, the biological functions of miR-128-3p in sepsis remain largely unknown, and its mechanism should be further investigated. This study aimed to determine the regulatory network of miR-128-3p and TGFBR2 in lipopolysaccharide (LPS)-induced sepsis. |
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ISSN: | 2391-5463 |