A green sample preparation method for the determination of bisphenols in honeys
Bisphenol A is the most studied compound due to its adverse effects on human health and is one of the most widely used products in contact materials worldwide. However, in recent years, due to stringent restrictions on the use of BPA, structural analogues are substituting BPA in the production of so...
Main Authors: | , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2023-06-01
|
Series: | Green Analytical Chemistry |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2772577423000113 |
_version_ | 1797347045490556928 |
---|---|
author | Angela Giorgia Potortì Federica Litrenta Benedetta Sgrò Giuseppa Di Bella Ambrogina Albergamo Hedi Ben Mansour Asma Beltifa Qada Benameur Vincenzo Lo Turco |
author_facet | Angela Giorgia Potortì Federica Litrenta Benedetta Sgrò Giuseppa Di Bella Ambrogina Albergamo Hedi Ben Mansour Asma Beltifa Qada Benameur Vincenzo Lo Turco |
author_sort | Angela Giorgia Potortì |
collection | DOAJ |
description | Bisphenol A is the most studied compound due to its adverse effects on human health and is one of the most widely used products in contact materials worldwide. However, in recent years, due to stringent restrictions on the use of BPA, structural analogues are substituting BPA in the production of some consumer products. A method based on the Micro-QuEChERS technique and ultra-high performance liquid chromatography coupled to tandem mass spectrometry (UHPLC-MS/MS) was proposed, derived from a previous method based on standard QuEChERS and HPLC-MS/MS. The proposed method was compared with the previous method using the analytical Eco-scale as a verification tool. The results highlight that the proposed method achieved a metric value of 79 points, higher than the required value of 75 points for 'excellent green analysis'. The method was then tested on Algerian and Tunisian honey samples of different floral origins. The results showed that the developed method was satisfactory in terms of recovery, sensitivity, and analysis time, showing good applicability even in a complex matrix such as honey. Low levels of contamination of residues of bisphenol-analogues were found and it can therefore be concluded that the samples analysed do not pose a health risk to consumers with regard to these compounds. |
first_indexed | 2024-03-08T11:41:52Z |
format | Article |
id | doaj.art-dd9260c85d224890a4e8f719943f2b60 |
institution | Directory Open Access Journal |
issn | 2772-5774 |
language | English |
last_indexed | 2024-03-08T11:41:52Z |
publishDate | 2023-06-01 |
publisher | Elsevier |
record_format | Article |
series | Green Analytical Chemistry |
spelling | doaj.art-dd9260c85d224890a4e8f719943f2b602024-01-25T05:24:17ZengElsevierGreen Analytical Chemistry2772-57742023-06-015100059A green sample preparation method for the determination of bisphenols in honeysAngela Giorgia Potortì0Federica Litrenta1Benedetta Sgrò2Giuseppa Di Bella3Ambrogina Albergamo4Hedi Ben Mansour5Asma Beltifa6Qada Benameur7Vincenzo Lo Turco8Department of Biomedical, Dental and Morphological and Functional Imaging Sciences (Biomorf), University of Messina, Polo Universitario dell'Annunziata, Messina 98168, ItalyDepartment of Biomedical, Dental and Morphological and Functional Imaging Sciences (Biomorf), University of Messina, Polo Universitario dell'Annunziata, Messina 98168, ItalyDepartment of Biomedical, Dental and Morphological and Functional Imaging Sciences (Biomorf), University of Messina, Polo Universitario dell'Annunziata, Messina 98168, ItalyDepartment of Biomedical, Dental and Morphological and Functional Imaging Sciences (Biomorf), University of Messina, Polo Universitario dell'Annunziata, Messina 98168, Italy; Corresponding author.Department of Biomedical, Dental and Morphological and Functional Imaging Sciences (Biomorf), University of Messina, Polo Universitario dell'Annunziata, Messina 98168, ItalyResearch Unit of Analysis and Process Applied on the Environment (APAE-UR17ES32) - Higher Institute of Applied Sciences and Technology, Universirty of Monastir, Mahdia, TunisiaResearch Unit of Analysis and Process Applied on the Environment (APAE-UR17ES32) - Higher Institute of Applied Sciences and Technology, Universirty of Monastir, Mahdia, Tunisia; Direction d'hygiène du milieu et de la protection de l'environnement à la direction régionale de santé de Mahdia, TunisieDepartment of Agronomy, Faculty of Nature and Life Sciences, University Abdelhamid Ibn Badis of Mostaganem, AlgeriaDepartment of Biomedical, Dental and Morphological and Functional Imaging Sciences (Biomorf), University of Messina, Polo Universitario dell'Annunziata, Messina 98168, ItalyBisphenol A is the most studied compound due to its adverse effects on human health and is one of the most widely used products in contact materials worldwide. However, in recent years, due to stringent restrictions on the use of BPA, structural analogues are substituting BPA in the production of some consumer products. A method based on the Micro-QuEChERS technique and ultra-high performance liquid chromatography coupled to tandem mass spectrometry (UHPLC-MS/MS) was proposed, derived from a previous method based on standard QuEChERS and HPLC-MS/MS. The proposed method was compared with the previous method using the analytical Eco-scale as a verification tool. The results highlight that the proposed method achieved a metric value of 79 points, higher than the required value of 75 points for 'excellent green analysis'. The method was then tested on Algerian and Tunisian honey samples of different floral origins. The results showed that the developed method was satisfactory in terms of recovery, sensitivity, and analysis time, showing good applicability even in a complex matrix such as honey. Low levels of contamination of residues of bisphenol-analogues were found and it can therefore be concluded that the samples analysed do not pose a health risk to consumers with regard to these compounds.http://www.sciencedirect.com/science/article/pii/S2772577423000113Bisphenol analoguesMicro extractionUHPL-MS/MSGreen analysisHoney samples |
spellingShingle | Angela Giorgia Potortì Federica Litrenta Benedetta Sgrò Giuseppa Di Bella Ambrogina Albergamo Hedi Ben Mansour Asma Beltifa Qada Benameur Vincenzo Lo Turco A green sample preparation method for the determination of bisphenols in honeys Green Analytical Chemistry Bisphenol analogues Micro extraction UHPL-MS/MS Green analysis Honey samples |
title | A green sample preparation method for the determination of bisphenols in honeys |
title_full | A green sample preparation method for the determination of bisphenols in honeys |
title_fullStr | A green sample preparation method for the determination of bisphenols in honeys |
title_full_unstemmed | A green sample preparation method for the determination of bisphenols in honeys |
title_short | A green sample preparation method for the determination of bisphenols in honeys |
title_sort | green sample preparation method for the determination of bisphenols in honeys |
topic | Bisphenol analogues Micro extraction UHPL-MS/MS Green analysis Honey samples |
url | http://www.sciencedirect.com/science/article/pii/S2772577423000113 |
work_keys_str_mv | AT angelagiorgiapotorti agreensamplepreparationmethodforthedeterminationofbisphenolsinhoneys AT federicalitrenta agreensamplepreparationmethodforthedeterminationofbisphenolsinhoneys AT benedettasgro agreensamplepreparationmethodforthedeterminationofbisphenolsinhoneys AT giuseppadibella agreensamplepreparationmethodforthedeterminationofbisphenolsinhoneys AT ambroginaalbergamo agreensamplepreparationmethodforthedeterminationofbisphenolsinhoneys AT hedibenmansour agreensamplepreparationmethodforthedeterminationofbisphenolsinhoneys AT asmabeltifa agreensamplepreparationmethodforthedeterminationofbisphenolsinhoneys AT qadabenameur agreensamplepreparationmethodforthedeterminationofbisphenolsinhoneys AT vincenzoloturco agreensamplepreparationmethodforthedeterminationofbisphenolsinhoneys AT angelagiorgiapotorti greensamplepreparationmethodforthedeterminationofbisphenolsinhoneys AT federicalitrenta greensamplepreparationmethodforthedeterminationofbisphenolsinhoneys AT benedettasgro greensamplepreparationmethodforthedeterminationofbisphenolsinhoneys AT giuseppadibella greensamplepreparationmethodforthedeterminationofbisphenolsinhoneys AT ambroginaalbergamo greensamplepreparationmethodforthedeterminationofbisphenolsinhoneys AT hedibenmansour greensamplepreparationmethodforthedeterminationofbisphenolsinhoneys AT asmabeltifa greensamplepreparationmethodforthedeterminationofbisphenolsinhoneys AT qadabenameur greensamplepreparationmethodforthedeterminationofbisphenolsinhoneys AT vincenzoloturco greensamplepreparationmethodforthedeterminationofbisphenolsinhoneys |