Clonorchis sinensis MF6p/HDM (CsMF6p/HDM) induces pro-inflammatory immune response in RAW 264.7 macrophage cells via NF-κB-dependent MAPK pathways

Clonorchis sinensis MF6p/HDM (CsMF6p/HDM) induces pro-inflammatory immune response in RAW 264.7 macrophage cells via NF-κB-dependent MAPK pathways

Abstract Background MF6p/host defense molecules (HDMs) are a broad family of small proteins secreted by helminth parasites. Although the physiological role of MF6p/HDMs in trematode parasites is not fully understood, their potential biological function in maintaining heme homeostasis and modulating...

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Bibliographic Details
Main Authors: Jung-Mi Kang, Won Gi Yoo, Hương Giang Lê, Jinyoung Lee, Woon-Mok Sohn, Byoung-Kuk Na
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Parasites & Vectors
Subjects:
Clonorchis sinensis
MF6p/host defense molecule
Lipopolysaccharide
Pro-inflammatory immune response
Structure
Docking
Online Access:https://doi.org/10.1186/s13071-020-3882-0

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