Genetic heterogeneity of infant acute leukemias
In this review we present current state of cytogenetic and molecular genetic diagnostics of various aberrations in infant acute leukemias together with our own experience in this field. A complex characteristic of acute leukemias was performed for both MLL-positive and MLL-negative patients. Genetic...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | Russian |
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ABV-press
2016-03-01
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| Series: | Онкогематология |
| Subjects: | |
| Online Access: | https://oncohematology.abvpress.ru/ongm/article/view/177 |
| _version_ | 1797855569571217408 |
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| author | G. A. Tsaur E. W. Fleischman A. M. Popov L. G. Fechina S. A. Rumyantsev |
| author_facet | G. A. Tsaur E. W. Fleischman A. M. Popov L. G. Fechina S. A. Rumyantsev |
| author_sort | G. A. Tsaur |
| collection | DOAJ |
| description | In this review we present current state of cytogenetic and molecular genetic diagnostics of various aberrations in infant acute leukemias together with our own experience in this field. A complex characteristic of acute leukemias was performed for both MLL-positive and MLL-negative patients. Genetic heterogeneity was shown. Common and rare cytogenetic and molecular genetic aberrations were presented. |
| first_indexed | 2024-04-09T20:25:58Z |
| format | Article |
| id | doaj.art-dd9578b3cb124bc99aef1222f0903321 |
| institution | Directory Open Access Journal |
| issn | 1818-8346 2413-4023 |
| language | Russian |
| last_indexed | 2024-04-09T20:25:58Z |
| publishDate | 2016-03-01 |
| publisher | ABV-press |
| record_format | Article |
| series | Онкогематология |
| spelling | doaj.art-dd9578b3cb124bc99aef1222f09033212023-03-30T20:15:11ZrusABV-pressОнкогематология1818-83462413-40232016-03-01111142310.17650/1818-8346-2016-11-1-14-23185Genetic heterogeneity of infant acute leukemiasG. A. Tsaur0E. W. Fleischman1A. M. Popov2L. G. Fechina3S. A. Rumyantsev4Regional Children Clinical Hospital No 1; 32 S. Deryabinoy St., Ekaterinburg, 620149, Russia Institute of Medical Cell Technologies; 22a Karla Marksa St., Ekaterinburg, 620026, Russia Ural Federal University named after the first President of Russia B. N. Yel’tsin; 19 Mira St., Ekaterinburg, 620002, RussiaN.N. Blokhin Russian Cancer Research Center, Ministry of Health of Russia; 23 Kashirskoe Shosse, Moscow, 115478, RussiaFederal Research Center of Pediatric Hematology, Oncology and Immunology named after Dmitriy Rogachev, Ministry of Health of Russia; 1 Samory Mashela St., Moscow, 117998, RussiaRegional Children Clinical Hospital No 1; 32 S. Deryabinoy St., Ekaterinburg, 620149, RussiaFederal Research Center of Pediatric Hematology, Oncology and Immunology named after Dmitriy Rogachev, Ministry of Health of Russia; 1 Samory Mashela St., Moscow, 117998, Russia N.I. Pirogov Russian National Research Medical University, Ministry of Health of Russia; 1 Ostrovityanova St., Moscow, 117997, RussiaIn this review we present current state of cytogenetic and molecular genetic diagnostics of various aberrations in infant acute leukemias together with our own experience in this field. A complex characteristic of acute leukemias was performed for both MLL-positive and MLL-negative patients. Genetic heterogeneity was shown. Common and rare cytogenetic and molecular genetic aberrations were presented.https://oncohematology.abvpress.ru/ongm/article/view/177infant acute leukemiacytogeneticsmolecular genetics |
| spellingShingle | G. A. Tsaur E. W. Fleischman A. M. Popov L. G. Fechina S. A. Rumyantsev Genetic heterogeneity of infant acute leukemias Онкогематология infant acute leukemia cytogenetics molecular genetics |
| title | Genetic heterogeneity of infant acute leukemias |
| title_full | Genetic heterogeneity of infant acute leukemias |
| title_fullStr | Genetic heterogeneity of infant acute leukemias |
| title_full_unstemmed | Genetic heterogeneity of infant acute leukemias |
| title_short | Genetic heterogeneity of infant acute leukemias |
| title_sort | genetic heterogeneity of infant acute leukemias |
| topic | infant acute leukemia cytogenetics molecular genetics |
| url | https://oncohematology.abvpress.ru/ongm/article/view/177 |
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