Construction and Immunogenicity of a Novel Multivalent Vaccine Prototype Based on Conserved Influenza Virus Antigens

Construction and Immunogenicity of a Novel Multivalent Vaccine Prototype Based on Conserved Influenza Virus Antigens

Influenza, an acute, highly contagious respiratory disease, remains a significant threat to public health. More effective vaccination strategies aimed at inducing broad cross-protection not only against seasonal influenza variants, but also zoonotic and emerging pandemic influenza strains are urgent...

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Bibliographic Details
Main Authors: Anna Kirsteina, Inara Akopjana, Janis Bogans, Ilva Lieknina, Juris Jansons, Dace Skrastina, Tatjana Kazaka, Kaspars Tars, Irina Isakova-Sivak, Daria Mezhenskaya, Tatiana Kotomina, Victoria Matyushenko, Larisa Rudenko, Andris Kazaks
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Vaccines
Subjects:
influenza
conserved antigens
hemagglutinin stalk
M2e protein
virus-like particles
protection
Online Access:https://www.mdpi.com/2076-393X/8/2/197

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