Cytotoxicity of the Sesquiterpene Lactone Spiciformin and Its Acetyl Derivative against the Human Leukemia Cell Lines U-937 and HL-60

Cytotoxicity of the Sesquiterpene Lactone Spiciformin and Its Acetyl Derivative against the Human Leukemia Cell Lines U-937 and HL-60

Spiciformin (<b>1</b>) is a sesquiterpene lactone with a germacrane skeleton that is found in two <i>Tanacetum</i> species endemic to the Canary Islands. In this study, the cytotoxicities of <b>1</b> and its acetyl derivative (<b>2</b>) were evaluated...

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Bibliographic Details
Main Authors: Ester Saavedra, Francisco Estévez-Sarmiento, Mercedes Said, José Luis Eiroa, Sara Rubio, José Quintana, Francisco Estévez
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:International Journal of Molecular Sciences
Subjects:
apoptosis
cytotoxicity
caspase
poly(ADP-ribose) polymerase
sesquiterpene lactone
Online Access:https://www.mdpi.com/1422-0067/21/8/2782

Internet

https://www.mdpi.com/1422-0067/21/8/2782

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