A case of lymphoepithelioma-like carcinoma in the uterine cervix
Lymphoepithelioma-like carcinoma occurring in the reproductive organs is a rare variant of squamous cell carcinoma, and this tumor of the uterine cervix accounts for 0.7% of all primary cervical uterine neoplasms. Associations with Epstein-Barr virus (EBV) and human papilloma virus (HPV) have been d...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2015-03-01
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| Series: | Rare Tumors |
| Subjects: | |
| Online Access: | http://www.pagepress.org/journals/index.php/rt/article/view/5688 |
| _version_ | 1828786352413474816 |
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| author | Kanetoshi Takebayashi Masakazu Nishida Harunobu Matsumoto Kaei Nasu Hisashi Narahara |
| author_facet | Kanetoshi Takebayashi Masakazu Nishida Harunobu Matsumoto Kaei Nasu Hisashi Narahara |
| author_sort | Kanetoshi Takebayashi |
| collection | DOAJ |
| description | Lymphoepithelioma-like carcinoma occurring in the reproductive organs is a rare variant of squamous cell carcinoma, and this tumor of the uterine cervix accounts for 0.7% of all primary cervical uterine neoplasms. Associations with Epstein-Barr virus (EBV) and human papilloma virus (HPV) have been demonstrated in some studies. Some investigators suggested that EBV has an important role in the initiation of lymphoepithelioma-like carcinoma in Asian women. Here we report the case of a 45-year-old Japanese woman, gravida 2 and parity 2. She was admitted due to severe atypical genital bleeding caused by uterine cervical cancer. A >60-mm tumor was detected at the uterine cervix, and no distal metastasis or swallowing of lymph nodes was revealed by magnetic resonance imaging and a computed tomography scan. The cervical cancer stage FIGO Ib2 was diagnosed, and a radical hysterectomy was performed for this malignant tumor. The <em>in situ</em> hybridization for EBV was negative. HVP infection was strongly suspected because the squamous cell carcinoma was observed macroscopically in the uterine cervix. The prognosis of uterine lymphoepithelioma-like carcinoma is thought to be better than those of other cervical cancer types, but careful follow-up at fixed intervals is recommended. The patient has been followed up for 4 months since her surgery, and no evidence of recurrence has been detected. |
| first_indexed | 2024-12-12T00:09:51Z |
| format | Article |
| id | doaj.art-dd9a426a8453408b8167bbc8a1ad3d7c |
| institution | Directory Open Access Journal |
| issn | 2036-3605 2036-3613 |
| language | English |
| last_indexed | 2024-12-12T00:09:51Z |
| publishDate | 2015-03-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Rare Tumors |
| spelling | doaj.art-dd9a426a8453408b8167bbc8a1ad3d7c2022-12-22T00:45:01ZengSAGE PublishingRare Tumors2036-36052036-36132015-03-017110.4081/rt.2015.56883045A case of lymphoepithelioma-like carcinoma in the uterine cervixKanetoshi Takebayashi0Masakazu Nishida1Harunobu Matsumoto2Kaei Nasu3Hisashi Narahara4Department of Obstetrics and Gynecology, Oita University, Faculty of MedicineDepartment of Obstetrics and Gynecology, Oita University, Faculty of MedicineDepartment of Obstetrics and Gynecology, Oita University, Faculty of MedicineDepartment of Obstetrics and Gynecology, Oita University, Faculty of MedicineDepartment of Obstetrics and Gynecology, Oita University, Faculty of MedicineLymphoepithelioma-like carcinoma occurring in the reproductive organs is a rare variant of squamous cell carcinoma, and this tumor of the uterine cervix accounts for 0.7% of all primary cervical uterine neoplasms. Associations with Epstein-Barr virus (EBV) and human papilloma virus (HPV) have been demonstrated in some studies. Some investigators suggested that EBV has an important role in the initiation of lymphoepithelioma-like carcinoma in Asian women. Here we report the case of a 45-year-old Japanese woman, gravida 2 and parity 2. She was admitted due to severe atypical genital bleeding caused by uterine cervical cancer. A >60-mm tumor was detected at the uterine cervix, and no distal metastasis or swallowing of lymph nodes was revealed by magnetic resonance imaging and a computed tomography scan. The cervical cancer stage FIGO Ib2 was diagnosed, and a radical hysterectomy was performed for this malignant tumor. The <em>in situ</em> hybridization for EBV was negative. HVP infection was strongly suspected because the squamous cell carcinoma was observed macroscopically in the uterine cervix. The prognosis of uterine lymphoepithelioma-like carcinoma is thought to be better than those of other cervical cancer types, but careful follow-up at fixed intervals is recommended. The patient has been followed up for 4 months since her surgery, and no evidence of recurrence has been detected.http://www.pagepress.org/journals/index.php/rt/article/view/5688uterine cervical cancer, lymphoepithelioma-like carcinoma, squamous cell carcinoma |
| spellingShingle | Kanetoshi Takebayashi Masakazu Nishida Harunobu Matsumoto Kaei Nasu Hisashi Narahara A case of lymphoepithelioma-like carcinoma in the uterine cervix Rare Tumors uterine cervical cancer, lymphoepithelioma-like carcinoma, squamous cell carcinoma |
| title | A case of lymphoepithelioma-like carcinoma in the uterine cervix |
| title_full | A case of lymphoepithelioma-like carcinoma in the uterine cervix |
| title_fullStr | A case of lymphoepithelioma-like carcinoma in the uterine cervix |
| title_full_unstemmed | A case of lymphoepithelioma-like carcinoma in the uterine cervix |
| title_short | A case of lymphoepithelioma-like carcinoma in the uterine cervix |
| title_sort | case of lymphoepithelioma like carcinoma in the uterine cervix |
| topic | uterine cervical cancer, lymphoepithelioma-like carcinoma, squamous cell carcinoma |
| url | http://www.pagepress.org/journals/index.php/rt/article/view/5688 |
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