<i>Let-7g</i> Upregulation Attenuated the KRAS–PI3K–Rac1–Akt Axis-Mediated Bioenergetic Functions

<i>Let-7g</i> Upregulation Attenuated the KRAS–PI3K–Rac1–Akt Axis-Mediated Bioenergetic Functions

The aberrant activation of signaling pathways contributes to cancer cells with metabolic reprogramming. Thus, targeting signaling modulators is considered a potential therapeutic strategy for cancer. Subcellular fractionation, coimmunoprecipitation, biochemical analysis, and gene manipulation experi...

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Bibliographic Details
Main Authors: Kuang-Chen Hung, Ni Tien, Da-Tian Bau, Chun-Hsu Yao, Chan-Hung Chen, Jiun-Long Yang, Meng-Liang Lin, Shih-Shun Chen
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Cells
Subjects:
bioenergetic metabolism
KRAS
<i>let-7g</i>
MCPIP1
naringenin
Online Access:https://www.mdpi.com/2073-4409/12/18/2313

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