Molecular mapping of a core transcriptional signature of microglia-specific genes in schizophrenia
Abstract Besides playing a central role in neuroinflammation, microglia regulate synaptic development and is involved in plasticity. Converging lines of evidence suggest that these different processes play a critical role in schizophrenia. Furthermore, previous studies reported altered transcription...
Main Authors: | Anna M. Fiorito, Eric Fakra, Guillaume Sescousse, El Chérif Ibrahim, Romain Rey |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2023-12-01
|
Series: | Translational Psychiatry |
Online Access: | https://doi.org/10.1038/s41398-023-02677-y |
Similar Items
-
Sex-specific transcriptional and proteomic signatures in schizophrenia
by: Jari Tiihonen, et al.
Published: (2019-09-01) -
Microglia sequelae: brain signature of innate immunity in schizophrenia
by: A. Catarina Rodrigues-Neves, et al.
Published: (2022-11-01) -
A Novel Microglia-Specific Transcriptional Signature Correlates With Behavioral Deficits in Neuropsychiatric Lupus
by: Hadijat M. Makinde, et al.
Published: (2020-02-01) -
Transcriptional signature in microglia associated with Aβ plaque phagocytosis
by: Alexandra Grubman, et al.
Published: (2021-05-01) -
Microglia-neuron interactions in schizophrenia
by: Sophia-Marie Hartmann, et al.
Published: (2024-03-01)