IDbSV: An Open-Access Repository for Monitoring SARS-CoV-2 Variations and Evolution
Ending COVID-19 pandemic requires a collaborative understanding of SARS-CoV-2 and COVID-19 mechanisms. Yet, the evolving nature of coronaviruses results in a continuous emergence of new variants of the virus. Central to this is the need for a continuous monitoring system able to detect potentially h...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2021-12-01
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| Series: | Frontiers in Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2021.765249/full |
| _version_ | 1818389081839632384 |
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| author | Abdelmounim Essabbar Souad Kartti Tarek Alouane Mohammed Hakmi Lahcen Belyamani Azeddine Ibrahimi |
| author_facet | Abdelmounim Essabbar Souad Kartti Tarek Alouane Mohammed Hakmi Lahcen Belyamani Azeddine Ibrahimi |
| author_sort | Abdelmounim Essabbar |
| collection | DOAJ |
| description | Ending COVID-19 pandemic requires a collaborative understanding of SARS-CoV-2 and COVID-19 mechanisms. Yet, the evolving nature of coronaviruses results in a continuous emergence of new variants of the virus. Central to this is the need for a continuous monitoring system able to detect potentially harmful variants of the virus in real-time. In this manuscript, we present the International Database of SARS-CoV-2 Variations (IDbSV), the result of ongoing efforts in curating, analyzing, and sharing comprehensive interpretation of SARS-CoV-2's genetic variations and variants. Through user-friendly interactive data visualizations, we aim to provide a novel surveillance tool to the scientific and public health communities. The database is regularly updated with new records through a 4-step workflow (1—Quality control of curated sequences, 2—Call of variations, 3—Functional annotation, and 4—Metadata association). To the best of our knowledge, IDbSV provides access to the largest repository of SARS-CoV-2 variations and the largest analysis of SARS-CoV-2 genomes with over 60 thousand annotated variations curated from the 1,808,613 genomes alongside their functional annotations, first known appearance, and associated genetic lineages, enabling a robust interpretation tool for SARS-CoV-2 variations to help understanding SARS-CoV-2 dynamics across the world. |
| first_indexed | 2024-12-14T04:36:04Z |
| format | Article |
| id | doaj.art-dd9ddfdb83894990881ac514077e3488 |
| institution | Directory Open Access Journal |
| issn | 2296-858X |
| language | English |
| last_indexed | 2024-12-14T04:36:04Z |
| publishDate | 2021-12-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj.art-dd9ddfdb83894990881ac514077e34882022-12-21T23:16:57ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2021-12-01810.3389/fmed.2021.765249765249IDbSV: An Open-Access Repository for Monitoring SARS-CoV-2 Variations and EvolutionAbdelmounim Essabbar0Souad Kartti1Tarek Alouane2Mohammed Hakmi3Lahcen Belyamani4Azeddine Ibrahimi5Medical Biotechnology Laboratory (MedBiotech), Bioinova Research Center, Rabat Medical and Pharmacy School, Mohammed Vth University, Rabat, MoroccoMedical Biotechnology Laboratory (MedBiotech), Bioinova Research Center, Rabat Medical and Pharmacy School, Mohammed Vth University, Rabat, MoroccoMedical Biotechnology Laboratory (MedBiotech), Bioinova Research Center, Rabat Medical and Pharmacy School, Mohammed Vth University, Rabat, MoroccoMedical Biotechnology Laboratory (MedBiotech), Bioinova Research Center, Rabat Medical and Pharmacy School, Mohammed Vth University, Rabat, MoroccoEmergency Department, Military Hospital Mohammed V, Rabat Medical & Pharmacy School, Mohammed Vth University, Rabat, MoroccoMedical Biotechnology Laboratory (MedBiotech), Bioinova Research Center, Rabat Medical and Pharmacy School, Mohammed Vth University, Rabat, MoroccoEnding COVID-19 pandemic requires a collaborative understanding of SARS-CoV-2 and COVID-19 mechanisms. Yet, the evolving nature of coronaviruses results in a continuous emergence of new variants of the virus. Central to this is the need for a continuous monitoring system able to detect potentially harmful variants of the virus in real-time. In this manuscript, we present the International Database of SARS-CoV-2 Variations (IDbSV), the result of ongoing efforts in curating, analyzing, and sharing comprehensive interpretation of SARS-CoV-2's genetic variations and variants. Through user-friendly interactive data visualizations, we aim to provide a novel surveillance tool to the scientific and public health communities. The database is regularly updated with new records through a 4-step workflow (1—Quality control of curated sequences, 2—Call of variations, 3—Functional annotation, and 4—Metadata association). To the best of our knowledge, IDbSV provides access to the largest repository of SARS-CoV-2 variations and the largest analysis of SARS-CoV-2 genomes with over 60 thousand annotated variations curated from the 1,808,613 genomes alongside their functional annotations, first known appearance, and associated genetic lineages, enabling a robust interpretation tool for SARS-CoV-2 variations to help understanding SARS-CoV-2 dynamics across the world.https://www.frontiersin.org/articles/10.3389/fmed.2021.765249/fullSARS-CoV-2COVID-19genomic variationsdatabasemutation |
| spellingShingle | Abdelmounim Essabbar Souad Kartti Tarek Alouane Mohammed Hakmi Lahcen Belyamani Azeddine Ibrahimi IDbSV: An Open-Access Repository for Monitoring SARS-CoV-2 Variations and Evolution Frontiers in Medicine SARS-CoV-2 COVID-19 genomic variations database mutation |
| title | IDbSV: An Open-Access Repository for Monitoring SARS-CoV-2 Variations and Evolution |
| title_full | IDbSV: An Open-Access Repository for Monitoring SARS-CoV-2 Variations and Evolution |
| title_fullStr | IDbSV: An Open-Access Repository for Monitoring SARS-CoV-2 Variations and Evolution |
| title_full_unstemmed | IDbSV: An Open-Access Repository for Monitoring SARS-CoV-2 Variations and Evolution |
| title_short | IDbSV: An Open-Access Repository for Monitoring SARS-CoV-2 Variations and Evolution |
| title_sort | idbsv an open access repository for monitoring sars cov 2 variations and evolution |
| topic | SARS-CoV-2 COVID-19 genomic variations database mutation |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2021.765249/full |
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