Candidate Gene Analysis Reveals Strong Association of CETP Variants With High Density Lipoprotein Cholesterol and PCSK9 Variants With Low Density Lipoprotein Cholesterol in Ghanaian Adults: An AWI-Gen Sub-Study

Candidate Gene Analysis Reveals Strong Association of CETP Variants With High Density Lipoprotein Cholesterol and PCSK9 Variants With Low Density Lipoprotein Cholesterol in Ghanaian Adults: An AWI-Gen Sub-Study

Variations in lipid levels are attributed partly to genetic factors. Genome-wide association studies (GWASs) mainly performed in European, African American and Asian cohorts have identified variants associated with LDL-C, HDL-C, total cholesterol (TC) and triglycerides (TG), but few studies have bee...

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Bibliographic Details
Main Authors: Godfred Agongo, Lucas Amenga-Etego, Engelbert A. Nonterah, Cornelius Debpuur, Ananyo Choudhury, Amy R. Bentley, Abraham R. Oduro, Charles N. Rotimi, Nigel J. Crowther, Michèle Ramsay, AWI-Gen and H3Africa, H3Africa
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Genetics
Subjects:
candidate gene
lipid
single nucleotide variant
Ghanaians
AWI-Gen
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2020.456661/full

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