Synthesis of Zinc Oxide Nanoparticles Using <i>Rubus fairholmianus</i> Root Extract and Their Activity against Pathogenic Bacteria
Recently, the biosynthesis of zinc oxide nanoparticles (ZnO NPs) from crude extracts and phytochemicals has attracted much attention. Green synthesis of NPs is cost-effective, eco-friendly, and is a promising alternative for chemical synthesis. This study involves ZnO NPs synthesis using <i>Ru...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-05-01
|
| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/26/10/3029 |
| _version_ | 1797533513131491328 |
|---|---|
| author | Naresh Kumar Rajendran Blassan P. George Nicolette N. Houreld Heidi Abrahamse |
| author_facet | Naresh Kumar Rajendran Blassan P. George Nicolette N. Houreld Heidi Abrahamse |
| author_sort | Naresh Kumar Rajendran |
| collection | DOAJ |
| description | Recently, the biosynthesis of zinc oxide nanoparticles (ZnO NPs) from crude extracts and phytochemicals has attracted much attention. Green synthesis of NPs is cost-effective, eco-friendly, and is a promising alternative for chemical synthesis. This study involves ZnO NPs synthesis using <i>Rubus fairholmianus</i> root extract (RE) as an efficient reducing agent. The UV spectrum of RE-ZnO NPs exhibited a peak at 357 nm due to intrinsic bandgap absorption and an XRD pattern that matches the ZnO crystal structure (JCPDS card no: 36-1451). The average particle size calculated from the Debye–Scherrer equation is 11.34 nm. SEM analysis showed that the RE-ZnO NPs spherical in shape with clusters (1–100 nm). The antibacterial activity of the NPs was tested against <i>Staphylococcus aureus</i> using agar well diffusion, minimum inhibitory concentration, and bacterial growth assay. The <i>R. fairholmianus</i> phytochemicals facilitate the synthesis of stable ZnO NPs and showed antibacterial activity. |
| first_indexed | 2024-03-10T11:16:35Z |
| format | Article |
| id | doaj.art-dda4229c3526438e8118ad42dc47a819 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-10T11:16:35Z |
| publishDate | 2021-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-dda4229c3526438e8118ad42dc47a8192023-11-21T20:25:42ZengMDPI AGMolecules1420-30492021-05-012610302910.3390/molecules26103029Synthesis of Zinc Oxide Nanoparticles Using <i>Rubus fairholmianus</i> Root Extract and Their Activity against Pathogenic BacteriaNaresh Kumar Rajendran0Blassan P. George1Nicolette N. Houreld2Heidi Abrahamse3Laser Research Centre, Faculty of Health Sciences, University of Johannesburg, P.O. Box 17011, Doornfontein, Johannesburg 2028, South AfricaLaser Research Centre, Faculty of Health Sciences, University of Johannesburg, P.O. Box 17011, Doornfontein, Johannesburg 2028, South AfricaLaser Research Centre, Faculty of Health Sciences, University of Johannesburg, P.O. Box 17011, Doornfontein, Johannesburg 2028, South AfricaLaser Research Centre, Faculty of Health Sciences, University of Johannesburg, P.O. Box 17011, Doornfontein, Johannesburg 2028, South AfricaRecently, the biosynthesis of zinc oxide nanoparticles (ZnO NPs) from crude extracts and phytochemicals has attracted much attention. Green synthesis of NPs is cost-effective, eco-friendly, and is a promising alternative for chemical synthesis. This study involves ZnO NPs synthesis using <i>Rubus fairholmianus</i> root extract (RE) as an efficient reducing agent. The UV spectrum of RE-ZnO NPs exhibited a peak at 357 nm due to intrinsic bandgap absorption and an XRD pattern that matches the ZnO crystal structure (JCPDS card no: 36-1451). The average particle size calculated from the Debye–Scherrer equation is 11.34 nm. SEM analysis showed that the RE-ZnO NPs spherical in shape with clusters (1–100 nm). The antibacterial activity of the NPs was tested against <i>Staphylococcus aureus</i> using agar well diffusion, minimum inhibitory concentration, and bacterial growth assay. The <i>R. fairholmianus</i> phytochemicals facilitate the synthesis of stable ZnO NPs and showed antibacterial activity.https://www.mdpi.com/1420-3049/26/10/3029zinc oxidegreen synthesisnanoparticlesantibacterial<i>Rubus fairholmianus</i> |
| spellingShingle | Naresh Kumar Rajendran Blassan P. George Nicolette N. Houreld Heidi Abrahamse Synthesis of Zinc Oxide Nanoparticles Using <i>Rubus fairholmianus</i> Root Extract and Their Activity against Pathogenic Bacteria Molecules zinc oxide green synthesis nanoparticles antibacterial <i>Rubus fairholmianus</i> |
| title | Synthesis of Zinc Oxide Nanoparticles Using <i>Rubus fairholmianus</i> Root Extract and Their Activity against Pathogenic Bacteria |
| title_full | Synthesis of Zinc Oxide Nanoparticles Using <i>Rubus fairholmianus</i> Root Extract and Their Activity against Pathogenic Bacteria |
| title_fullStr | Synthesis of Zinc Oxide Nanoparticles Using <i>Rubus fairholmianus</i> Root Extract and Their Activity against Pathogenic Bacteria |
| title_full_unstemmed | Synthesis of Zinc Oxide Nanoparticles Using <i>Rubus fairholmianus</i> Root Extract and Their Activity against Pathogenic Bacteria |
| title_short | Synthesis of Zinc Oxide Nanoparticles Using <i>Rubus fairholmianus</i> Root Extract and Their Activity against Pathogenic Bacteria |
| title_sort | synthesis of zinc oxide nanoparticles using i rubus fairholmianus i root extract and their activity against pathogenic bacteria |
| topic | zinc oxide green synthesis nanoparticles antibacterial <i>Rubus fairholmianus</i> |
| url | https://www.mdpi.com/1420-3049/26/10/3029 |
| work_keys_str_mv | AT nareshkumarrajendran synthesisofzincoxidenanoparticlesusingirubusfairholmianusirootextractandtheiractivityagainstpathogenicbacteria AT blassanpgeorge synthesisofzincoxidenanoparticlesusingirubusfairholmianusirootextractandtheiractivityagainstpathogenicbacteria AT nicolettenhoureld synthesisofzincoxidenanoparticlesusingirubusfairholmianusirootextractandtheiractivityagainstpathogenicbacteria AT heidiabrahamse synthesisofzincoxidenanoparticlesusingirubusfairholmianusirootextractandtheiractivityagainstpathogenicbacteria |