Pharmacological targeting of membrane rigidity: implications on cancer cell migration and invasion

Pharmacological targeting of membrane rigidity: implications on cancer cell migration and invasion

The invasive potential of cancer cells strongly depends on cellular stiffness, a physical quantity that is not only regulated by the mechanical impact of the cytoskeleton but also influenced by the membrane rigidity. To analyze the specific role of membrane rigidity in cancer progression, we treated...

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Bibliographic Details
Main Authors: Simone Braig, B U Sebastian Schmidt, Katharina Stoiber, Chris Händel, Till Möhn, Oliver Werz, Rolf Müller, Stefan Zahler, Andreas Koeberle, Josef A Käs, Angelika M Vollmar
Format: Article
Language:English
Published: IOP Publishing 2015-01-01
Series:New Journal of Physics
Subjects:
membrane biophysics
biomechanics
physics of cancer
87.16.D- or 87.16.dm
Online Access:https://doi.org/10.1088/1367-2630/17/8/083007

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