LABORATORY PREDICTORS OF RAPID HIV DEVELOPMENT IN CHILDREN
91 children vertically infected with HIV were examined. 26% of the patients, developed HIV infection rapidly with its subsequent development into AIDS in the first two years of life. Multifactorial logistic regression model demonstrated that independent predictors of rapid HIV-infection progression...
Main Authors: | , |
---|---|
Format: | Article |
Language: | Russian |
Published: |
LLC "Diagnostics and Vaccines"
2015-08-01
|
Series: | Детские инфекции (Москва) |
Subjects: | |
Online Access: | https://detinf.elpub.ru/jour/article/view/68 |
Summary: | 91 children vertically infected with HIV were examined. 26% of the patients, developed HIV infection rapidly with its subsequent development into AIDS in the first two years of life. Multifactorial logistic regression model demonstrated that independent predictors of rapid HIV-infection progression in children were HIV blood viral load 300 000 cop./ml and CD4+-lymphocytes count 20% in the age of six months. The use of HIV blood viral load level as a prognostic test is preferred because of higher sensitivity (91,3%) and specificity (97,1%). |
---|---|
ISSN: | 2072-8107 |