LABORATORY PREDICTORS OF RAPID HIV DEVELOPMENT IN CHILDREN

91 children vertically infected with HIV were examined. 26% of the patients, developed HIV infection rapidly with its subsequent development into AIDS in the first two years of life. Multifactorial logistic regression model demonstrated that independent predictors of rapid HIV-infection progression...

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Bibliographic Details
Main Authors: V. B. Denisenko, E. N. Simovanyan
Format: Article
Language:Russian
Published: LLC "Diagnostics and Vaccines" 2015-08-01
Series:Детские инфекции (Москва)
Subjects:
Online Access:https://detinf.elpub.ru/jour/article/view/68
Description
Summary:91 children vertically infected with HIV were examined. 26% of the patients, developed HIV infection rapidly with its subsequent development into AIDS in the first two years of life. Multifactorial logistic regression model demonstrated that independent predictors of rapid HIV-infection progression in children were HIV blood viral load 300 000 cop./ml and CD4+-lymphocytes count 20% in the age of six months. The use of HIV blood viral load level as a prognostic test is preferred because of higher sensitivity (91,3%) and specificity (97,1%).
ISSN:2072-8107